Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (52) GO Terms (5) Nucleotides (60) Proteins (36) Interactants (120) Wiki
XB-GENEPAGE-5824075

Papers associated with slc6a1



???displayGene.coCitedPapers???

???pagination.result.count???

???pagination.result.page??? 1 2 ???pagination.result.next???

Sort Newest To Oldest Sort Oldest To Newest

Expression of a mouse brain cDNA encoding novel gamma-aminobutyric acid transporter., Lopez-Corcuera B, Liu QR, Mandiyan S, Nelson H, Nelson N., J Biol Chem. September 5, 1992; 267 (25): 17491-3.

Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected]., Liu QR, López-Corcuera B, Mandiyan S, Nelson H, Nelson N., J Biol Chem. January 25, 1993; 268 (3): 2106-12.

Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes., Mager S, Naeve J, Quick M, Labarca C, Davidson N, Lester HA., Neuron. February 1, 1993; 10 (2): 177-88.

Phorbol ester-induced inhibition of GABA uptake by synaptosomes and by Xenopus oocytes expressing GABA transporter (GAT1)., Osawa I, Saito N, Koga T, Tanaka C., Neurosci Res. May 1, 1994; 19 (3): 287-93.

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter., Corey JL, Davidson N, Lester HA, Brecha N, Quick MW., J Biol Chem. May 20, 1994; 269 (20): 14759-67.

Membrane transport mechanisms probed by capacitance measurements with megahertz voltage clamp., Lu CC, Kabakov A, Markin VS, Mager S, Frazier GA, Hilgemann DW., Proc Natl Acad Sci U S A. November 21, 1995; 92 (24): 11220-4.

Short external loops as potential substrate binding site of gamma-aminobutyric acid transporters., Tamura S, Nelson H, Tamura A, Nelson N., J Biol Chem. December 1, 1995; 270 (48): 28712-5.

Ion binding and permeation at the GABA transporter GAT1., Mager S, Kleinberger-Doron N, Keshet GI, Davidson N, Kanner BI, Lester HA., J Neurosci. September 1, 1996; 16 (17): 5405-14.

Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1., Quick MW, Corey JL, Davidson N, Lester HA., J Neurosci. May 1, 1997; 17 (9): 2967-79.

Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation., Yu N, Cao Y, Mager S, Lester HA., FEBS Lett. April 17, 1998; 426 (2): 174-8.

Effect of mutation of glycosylation sites on the Na+ dependence of steady-state and transient currents generated by the neuronal GABA transporter., Liu Y, Eckstein-Ludwig U, Fei J, Schwarz W., Biochim Biophys Acta. December 9, 1998; 1415 (1): 246-54.

Passive water and ion transport by cotransporters., Loo DD, Hirayama BA, Meinild AK, Chandy G, Zeuthen T, Wright EM., J Physiol. July 1, 1999; 518 ( Pt 1) 195-202.

Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs., Eckstein-Ludwig U, Fei J, Schwarz W., Br J Pharmacol. September 1, 1999; 128 (1): 92-102.

GAT1 (GABA:Na+:Cl-) cotransport function. Database reconstruction with an alternating access model., Hilgemann DW, Lu CC., J Gen Physiol. September 1, 1999; 114 (3): 459-75.                                

GAT1 (GABA:Na+:Cl-) cotransport function. Kinetic studies in giant Xenopus oocyte membrane patches., Lu CC, Hilgemann DW., J Gen Physiol. September 1, 1999; 114 (3): 445-57.                  

GAT1 (GABA:Na+:Cl-) cotransport function. Steady state studies in giant Xenopus oocyte membrane patches., Lu CC, Hilgemann DW., J Gen Physiol. September 1, 1999; 114 (3): 429-44.                        

An intermediate state of the gamma-aminobutyric acid transporter GAT1 revealed by simultaneous voltage clamp and fluorescence., Li M, Farley RA, Lester HA., J Gen Physiol. April 1, 2000; 115 (4): 491-508.                              

Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A., Deken SL, Beckman ML, Boos L, Quick MW., Nat Neurosci. October 1, 2000; 3 (10): 998-1003.

Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1., Loo DD, Eskandari S, Boorer KJ, Sarkar HK, Wright EM., J Biol Chem. December 1, 2000; 275 (48): 37414-22.

Syntaxin 1A up-regulates GABA transporter expression by subcellular redistribution., Horton N, Quick MW., Mol Membr Biol. January 1, 2001; 18 (1): 39-44.

Transport of L-carnitine in isolated cerebral cortex neurons., Wawrzeńczyk A, Sacher A, Mac M, Nałecz MJ, Nałecz KA., Eur J Biochem. April 1, 2001; 268 (7): 2091-8.

Differential effect of pH on sodium binding by the various GABA transporters expressed in Xenopus oocytes., Grossman TR, Nelson N., FEBS Lett. September 11, 2002; 527 (1-3): 125-32.

Effect of sodium lithium and proton concentrations on the electrophysiological properties of the four mouse GABA transporters expressed in Xenopus oocytes., Grossman TR, Nelson N., Neurochem Int. January 1, 2003; 43 (4-5): 431-43.

Down-regulation of GABA-transporter function by hippocampal translation products: its possible role in epilepsy., Fueta Y, Vasilets LA, Takeda K, Kawamura M, Schwarz W., Neuroscience. January 1, 2003; 118 (2): 371-8.

K+ amino acid transporter KAAT1 mutant Y147F has increased transport activity and altered substrate selectivity., Liu Z, Stevens BR, Feldman DH, Hediger MA, Harvey WR., J Exp Biol. January 1, 2003; 206 (Pt 2): 245-54.

The anticonvulsant valproate increases the turnover rate of gamma-aminobutyric acid transporters., Whitlow RD, Sacher A, Loo DD, Nelson N, Eskandari S., J Biol Chem. May 16, 2003; 278 (20): 17716-26.

Syntaxin 1A inhibits GABA flux, efflux, and exchange mediated by the rat brain GABA transporter GAT1., Wang D, Deken SL, Whitworth TL, Quick MW., Mol Pharmacol. October 1, 2003; 64 (4): 905-13.

Modulation of Na(+),K(+) pumping and neurotransmitter uptake by beta-amyloid., Gu QB, Zhao JX, Fei J, Schwarz W., Neuroscience. January 1, 2004; 126 (1): 61-7.

Intracellular domains of a rat brain GABA transporter that govern transport., Hansra N, Arya S, Quick MW., J Neurosci. April 21, 2004; 24 (16): 4082-7.

Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4)., Karakossian MH, Spencer SR, Gomez AQ, Padilla OR, Sacher A, Loo DD, Nelson N, Eskandari S., J Membr Biol. January 1, 2005; 203 (2): 65-82.

Antiepileptic action induced by a combination of vigabatrin and tiagabine., Fueta Y, Kunugita N, Schwarz W., Neuroscience. January 1, 2005; 132 (2): 335-45.

Relations between substrate affinities and charge equilibration rates in the rat GABA cotransporter GAT1., Soragna A, Bossi E, Giovannardi S, Pisani R, Peres A., J Physiol. January 15, 2005; 562 (Pt 2): 333-45.

Expression and transport function of the glutamate transporter EAAC1 in Xenopus oocytes is regulated by syntaxin 1A., Zhu Y, Fei J, Schwarz W., J Neurosci Res. February 15, 2005; 79 (4): 503-8.

Mediation of highly concentrative uptake of pregabalin by L-type amino acid transport in Chinese hamster ovary and Caco-2 cells., Su TZ, Feng MR, Weber ML., J Pharmacol Exp Ther. June 1, 2005; 313 (3): 1406-15.

Identification and selective inhibition of the channel mode of the neuronal GABA transporter 1., Krause S, Schwarz W., Mol Pharmacol. December 1, 2005; 68 (6): 1728-35.

AtGAT1, a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana., Meyer A, Eskandari S, Grallath S, Rentsch D., J Biol Chem. March 17, 2006; 281 (11): 7197-204.

The role of early lineage in GABAergic and glutamatergic cell fate determination in Xenopus laevis., Li M, Sipe CW, Hoke K, August LL, Wright MA, Saha MS., J Comp Neurol. April 20, 2006; 495 (6): 645-57.                    

N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a., Wiles AL, Pearlman RJ, Rosvall M, Aubrey KR, Vandenberg RJ., J Neurochem. November 1, 2006; 99 (3): 781-6.

Turnover rate of the gamma-aminobutyric acid transporter GAT1., Gonzales AL, Lee W, Spencer SR, Oropeza RA, Chapman JV, Ku JY, Eskandari S., J Membr Biol. December 1, 2007; 220 (1-3): 33-51.

Inhibitors of the gamma-aminobutyric acid transporter 1 (GAT1) do not reveal a channel mode of conduction., Matthews E, Rahnama-Vaghef A, Eskandari S., Neurochem Int. December 1, 2009; 55 (8): 732-40.

Passive water permeability of some wild type and mutagenized amino acid cotransporters of the SLC6/NSS family expressed in Xenopus laevis oocytes., Santacroce M, Castagna M, Sacchi VF., Comp Biochem Physiol A Mol Integr Physiol. August 1, 2010; 156 (4): 509-17.

GABA reverse transport by the neuronal cotransporter GAT1: influence of internal chloride depletion., Bertram S, Cherubino F, Bossi E, Castagna M, Peres A., Am J Physiol Cell Physiol. November 1, 2011; 301 (5): C1064-73.

An integrated field-effect microdevice for monitoring membrane transport in Xenopus laevis oocytes via lateral proton diffusion., Schaffhauser DF, Patti M, Goda T, Miyahara Y, Forster IC, Dittrich PS., PLoS One. January 1, 2012; 7 (7): e39238.          

Inhibition of Activity of GABA Transporter GAT1 by δ-Opioid Receptor., Pu L, Xu N, Xia P, Gu Q, Ren S, Fucke T, Pei G, Schwarz W., Evid Based Complement Alternat Med. January 1, 2012; 2012 818451.              

Pre-steady-state and reverse transport currents in the GABA transporter GAT1., Cherubino F, Bertram S, Bossi E, Peres A., Am J Physiol Cell Physiol. April 15, 2012; 302 (8): C1096-108.

Using lithium to probe sequential cation interactions with GAT1., Meinild AK, Forster IC., Am J Physiol Cell Physiol. June 1, 2012; 302 (11): C1661-75.

An inverse relationship links temperature and substrate apparent affinity in the ion-coupled cotransporters rGAT1 and KAAT1., Peres A, Vollero A, Margheritis E, D'Antoni F, Bossi E., Int J Mol Sci. November 22, 2012; 13 (12): 15565-74.      

Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue., Omoto JJ, Maestas MJ, Rahnama-Vaghef A, Choi YE, Salto G, Sanchez RV, Anderson CM, Eskandari S., J Membr Biol. December 1, 2012; 245 (12): 841-57.                  

Evidence for a Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters., Willford SL, Anderson CM, Spencer SR, Eskandari S., J Membr Biol. August 1, 2015; 248 (4): 795-810.

A convergent molecular network underlying autism and congenital heart disease., Rosenthal SB, Willsey HR, Xu Y, Xu Y, Mei Y, Dea J, Wang S, Curtis C, Sempou E, Khokha MK, Chi NC, Willsey AJ, Fisch KM, Ideker T., Cell Syst. November 17, 2021; 12 (11): 1094-1107.e6.            

???pagination.result.page??? 1 2 ???pagination.result.next???