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Summary Expression Phenotypes Gene Literature (106) GO Terms (4) Nucleotides (57) Proteins (33) Interactants (107) Wiki

Papers associated with kcna1

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1 paper(s) referencing morpholinos

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Selective block of human Kv1.1 channels and an epilepsy-associated gain-of-function mutation by AETX-K peptide., Zhao R, Qasim A, Sophanpanichkul P, Dai H, Nayak M, Sher I, Chill J, Goldstein SAN., FASEB J. January 1, 2024; 38 (1): e23381.              

Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K+ channels., Bassetto CA, Carvalho-de-Souza JL, Bezanilla F., Elife. February 23, 2021; 10             

A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel., Zhao J, Petitjean D, Haddad GA, Batulan Z, Blunck R., Int J Mol Sci. October 14, 2020; 21 (20):                 

Electromechanical coupling of the Kv1.1 voltage-gated K+ channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker., Hasan S, Megaro A, Cenciarini M, Coretti L, Botti FM, Imbrici P, Steinbusch HWM, Hunter T, Hunter G, Pessia M, D'Adamo MC., Pflugers Arch. July 1, 2020; 472 (7): 899-909.

Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine., Manville RW, Abbott GW., J Pharmacol Exp Ther. June 1, 2020; 373 (3): 391-401.

Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket., Manville RW, Abbott GW., Nat Commun. September 21, 2018; 9 (1): 3845.                  

Direct neurotransmitter activation of voltage-gated potassium channels., Manville RW, Papanikolaou M, Abbott GW., Nat Commun. May 10, 2018; 9 (1): 1847.            

Congruent pattern of accessibility identifies minimal pore gate in a non-symmetric voltage-gated sodium channel., Oelstrom K, Chanda B., Nat Commun. May 17, 2016; 7 11608.

Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1: AN INTEGRATED TRANSCRIPTOMIC AND PROTEOMIC STUDY., Kuzmenkov AI, Vassilevski AA, Kudryashova KS, Nekrasova OV, Peigneur S, Tytgat J, Feofanov AV, Kirpichnikov MP, Grishin EV., J Biol Chem. May 8, 2015; 290 (19): 12195-209.

RNA editing in the central cavity as a mechanism to regulate surface expression of the voltage-gated potassium channel Kv1.1., Streit AK, Matschke LA, Dolga AM, Rinné S, Decher N., J Biol Chem. September 26, 2014; 289 (39): 26762-26771.

Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates., Yajima H, Suzuki M, Ochi H, Ikeda K, Sato S, Yamamura K, Ogino H, Ueno N, Kawakami K., BMC Biol. May 29, 2014; 12 40.                        

Molecular cloning, bioinformatics analysis and functional characterization of HWTX-XI toxin superfamily from the spider Ornithoctonus huwena., Jiang L, Deng M, Duan Z, Tang X, Liang S., Peptides. April 1, 2014; 54 9-18.

Coexpression of auxiliary Kvβ2 subunits with Kv1.1 channels is required for developmental acquisition of unique firing properties of zebrafish Mauthner cells., Watanabe T, Shimazaki T, Mishiro A, Suzuki T, Hirata H, Tanimoto M, Oda Y., J Neurophysiol. March 1, 2014; 111 (6): 1153-64.

Synthesis of the non-peptidic snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT)(2), its lower and higher thio homologs and their ability to modulate potassium ion channels., Gao D, Sand R, Fu H, Sharmin N, Gallin WJ, Hall DG., Bioorg Med Chem Lett. October 15, 2013; 23 (20): 5503-6.

Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their α subunits., Al-Sabi A, Kaza SK, Dolly JO, Wang J., Biochem J. August 15, 2013; 454 (1): 101-8.

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel., Pless SA, Niciforovic AP, Galpin JD, Nunez JJ, Kurata HT, Ahern CA., Nat Commun. January 1, 2013; 4 1784.              

Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures., Ishida S, Sakamoto Y, Nishio T, Baulac S, Kuwamura M, Ohno Y, Takizawa A, Kaneko S, Serikawa T, Mashimo T., Dev Biol. January 30, 2012; 1435 154-66.

Episodic ataxias 1 and 2., Baloh RW., Handb Clin Neurol. January 1, 2012; 103 595-602.

Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain., Imbrici P, D'Adamo MC, Grottesi A, Biscarini A, Pessia M., Am J Physiol Cell Physiol. June 1, 2011; 300 (6): C1314-22.

RNA editing of Kv1.1 channels may account for reduced ictogenic potential of 4-aminopyridine in chronic epileptic rats., Streit AK, Derst C, Wegner S, Heinemann U, Zahn RK, Decher N., Epilepsia. March 1, 2011; 52 (3): 645-8.

Jingzhaotoxin-IX, a novel gating modifier of both sodium and potassium channels from Chinese tarantula Chilobrachys jingzhao., Deng M, Kuang F, Sun Z, Tao H, Cai T, Zhong L, Chen Z, Xiao Y, Liang S., Neuropharmacology. August 1, 2009; 57 (2): 77-87.

Syntaxin modulates Kv1.1 through dual action on channel surface expression and conductance., Feinshreiber L, Chikvashvili D, Michaelevski I, Lotan I., Biochemistry. May 19, 2009; 48 (19): 4109-14.

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties., Imbrici P, Grottesi A, D'Adamo MC, Mannucci R, Tucker SJ, Pessia M., Channels (Austin). January 1, 2009; 3 (1): 39-45.

A novel KCNA1 mutation identified in an Italian family affected by episodic ataxia type 1., Imbrici P, Gualandi F, D'Adamo MC, Masieri MT, Cudia P, De Grandis D, Mannucci R, Nicoletti I, Tucker SJ, Ferlini A, Pessia M., Neuroscience. December 2, 2008; 157 (3): 577-87.

A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes., Abbas N, Belghazi M, Abdel-Mottaleb Y, Tytgat J, Bougis PE, Martin-Eauclaire MF., Biochem Biophys Res Commun. November 21, 2008; 376 (3): 525-30.

Hemitoxin, the first potassium channel toxin from the venom of the Iranian scorpion Hemiscorpius lepturus., Srairi-Abid N, Shahbazzadeh D, Chatti I, Mlayah-Bellalouna S, Mejdoub H, Borchani L, Benkhalifa R, Akbari A, El Ayeb M., FEBS J. September 1, 2008; 275 (18): 4641-50.

OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae., Abdel-Mottaleb Y, Vandendriessche T, Clynen E, Landuyt B, Jalali A, Vatanpour H, Schoofs L, Tytgat J., Toxicon. June 15, 2008; 51 (8): 1424-30.

Functional coupling between the Kv1.1 channel and aldoketoreductase Kvbeta1., Pan Y, Weng J, Cao Y, Bhosle RC, Zhou M., J Biol Chem. March 28, 2008; 283 (13): 8634-42.

Peripheral nerve hyperexcitability due to dominant-negative KCNQ2 mutations., Wuttke TV, Jurkat-Rott K, Paulus W, Garncarek M, Lehmann-Horn F, Lerche H., Neurology. November 27, 2007; 69 (22): 2045-53.

Interaction of syntaxin with a single Kv1.1 channel: a possible mechanism for modulating neuronal excitability., Michaelevski I, Korngreen A, Lotan I., Pflugers Arch. June 1, 2007; 454 (3): 477-94.

Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia., Chen H, von Hehn C, Kaczmarek LK, Ment LR, Pober BR, Hisama FM., Neurogenetics. April 1, 2007; 8 (2): 131-5.      

Episodic ataxia type 1 mutation F184C alters Zn2+-induced modulation of the human K+ channel Kv1.4-Kv1.1/Kvbeta1.1., Imbrici P, D'Adamo MC, Cusimano A, Pessia M., Am J Physiol Cell Physiol. February 1, 2007; 292 (2): C778-87.

Episodic ataxia type 1 mutations in the KCNA1 gene impair the fast inactivation properties of the human potassium channels Kv1.4-1.1/Kvbeta1.1 and Kv1.4-1.1/Kvbeta1.2., Imbrici P, D'Adamo MC, Kullmann DM, Pessia M., Eur J Neurosci. December 1, 2006; 24 (11): 3073-83.

A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction., Persson AS, Klement G, Almgren M, Sahlholm K, Nilsson J, Petersson S, Arhem P, Schalling M, Lavebratt C., BMC Neurosci. November 23, 2005; 6 65.          

Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels., Yan L, Herrington J, Goldberg E, Dulski PM, Bugianesi RM, Slaughter RS, Banerjee P, Brochu RM, Priest BT, Kaczorowski GJ, Rudy B, Garcia ML., Mol Pharmacol. May 1, 2005; 67 (5): 1513-21.

Functional coupling of intracellular calcium and inactivation of voltage-gated Kv1.1/Kvbeta1.1 A-type K+ channels., Jow F, Zhang ZH, Kopsco DC, Carroll KC, Wang K., Proc Natl Acad Sci U S A. October 26, 2004; 101 (43): 15535-40.

An episodic ataxia type-1 mutation in the S1 segment sensitises the hKv1.1 potassium channel to extracellular Zn2+., Cusimano A, Cristina D'Adamo M, Pessia M., FEBS Lett. October 8, 2004; 576 (1-2): 237-44.

Molecular cloning and expression of a Kv1.1-like potassium channel from the electric organ of Electrophorus electricus., Thornhill WB, Watanabe I, Sutachan JJ, Wu MB, Wu X, Zhu J, Recio-Pinto E., J Membr Biol. November 1, 2003; 196 (1): 1-8.

KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels., Grunnet M, Rasmussen HB, Hay-Schmidt A, Rosenstierne M, Klaerke DA, Olesen SP, Jespersen T., Biophys J. September 1, 2003; 85 (3): 1525-37.

Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels., M'Barek S, Mosbah A, Sandoz G, Fajloun Z, Olamendi-Portugal T, Rochat H, Sampieri F, Guijarro JI, Mansuelle P, Delepierre M, De Waard M, Sabatier JM., Eur J Biochem. September 1, 2003; 270 (17): 3583-92.

Local anesthetic block of Kv channels: role of the S6 helix and the S5-S6 linker for bupivacaine action., Nilsson J, Madeja M, Arhem P., Mol Pharmacol. June 1, 2003; 63 (6): 1417-29.

Early embryonic expression of ion channels and pumps in chick and Xenopus development., Rutenberg J, Cheng SM, Levin M., Dev Dyn. December 1, 2002; 225 (4): 469-84.                            

Modulation of a brain voltage-gated K+ channel by syntaxin 1A requires the physical interaction of Gbetagamma with the channel., Michaelevski I, Chikvashvili D, Tsuk S, Fili O, Lohse MJ, Singer-Lahat D, Lotan I., J Biol Chem. September 20, 2002; 277 (38): 34909-17.

Episodic ataxia type 1 mutations in the human Kv1.1 potassium channel alter hKvbeta 1-induced N-type inactivation., Maylie B, Bissonnette E, Virk M, Adelman JP, Maylie JG., J Neurosci. June 15, 2002; 22 (12): 4786-93.

Characteristics of brain Kv1 channels tailored to mimic native counterparts by tandem linkage of alpha subunits: implications for K+ channelopathies., Akhtar S, Shamotienko O, Papakosta M, Ali F, Dolly JO., J Biol Chem. May 10, 2002; 277 (19): 16376-82.

Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2)., McCormack K, Connor JX, Zhou L, Ho LL, Ganetzky B, Chiu SY, Messing A., J Biol Chem. April 12, 2002; 277 (15): 13219-28.

Variable K(+) channel subunit dysfunction in inherited mutations of KCNA1., Rea R, Spauschus A, Eunson LH, Hanna MG, Kullmann DM., J Physiol. January 1, 2002; 538 (Pt 1): 5-23.

Functional and molecular expression of a voltage-dependent K(+) channel (Kv1.1) in interstitial cells of Cajal., Hatton WJ, Mason HS, Carl A, Doherty P, Latten MJ, Kenyon JL, Sanders KM, Horowitz B., J Physiol. June 1, 2001; 533 (Pt 2): 315-27.

Gallamine triethiodide selectively blocks voltage-gated potassium channels in Ranvier nodes., Hinck D, Wulff H, Koppenhöfer E., Gen Physiol Biophys. March 1, 2001; 20 (1): 83-95.

Expression cloning of KCRF, a potassium channel regulatory factor., Keren-Raifman T, Ivanina T, Bismuth Y, Dascal N., Biochem Biophys Res Commun. August 11, 2000; 274 (3): 852-8.

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