otx2 Expression

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Summary

Expression

Phenotypes

Gene Literature (570)

XB-GENEPAGE-485219

Gene Symbol: otx2

Gene Name: orthodenticle homeobox 2

Anatomy terms

adenohypophyseal placode animal cap animal hemisphere anterior anterior neural fold anterior neural ridge anterior neural tube anterior placodal area axial mesoderm bipolar neuron blastopore lip brain ... [+]

Anatomy stages

unfertilized egg stage to NF stage 66

RNA-Seq and EST Transcriptome profiles	tropicalis	laevis.L	laevis.S
RNA-Seq stage profile	Data from Owens et al. 2016	Data from Session et al. 2016	Data from Session et al. 2016
GEO data		otx2.L	otx2.S
Microarray Data	Data from Yanai et al. 2011	Data from Yanai et al. 2011	Data from Yanai et al. 2011

Stage and Tissue Profiles

Source: Owens et al. 2016 (tropicalis)

Source: Session et al. 2016 (laevis)

Experimental Regulation (via RNA-seq)

Source: Ding et al. 2017 (laevis)

Summary Images

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NF stage 7 to NF stage 9	NF stage 10.5	NF stage 10.5 to NF stage 11	NF stage 20	NF stage 23	1 more [+]

Community Submitted Images

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NF stage 7 to NF stage 9	NF stage 7 to NF stage 9	NF stage 7 to NF stage 9	NF stage 7 to NF stage 9	NF stage 10	33 more [+]

Literature Images

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oocyte stage I Betley, et al. 2002	NF stage 10 Griffin, et al. 2018	NF stage 10 Fletcher, et al. 2008	NF stage 10 to NF stage 10.25 Liu, et al. 2012	NF stage 10.5 Yelin, et al. 2005	311 more [+]

NF stage 10	NF stage 10	NF stage 10	NF stage 10.5	NF stage 10.5
NF stage 10.5 to NF stage 11	NF stage 13	NF stage 13	NF stage 15	NF stage 15
NF stage 15	NF stage 15	NF stage 15	NF stage 16	NF stage 18
NF stage 20	NF stage 23	NF stage 23	NF stage 23	NF stage 23
NF stage 23	NF stage 23	NF stage 23	NF stage 25	NF stage 25
NF stage 25	NF stage 25	NF stage 25	NF stage 25	NF stage 25
NF stage 29 and 30	NF stage 32	NF stage 40

NF stage 10.5 In der Rieden, et al. 2010	NF stage 10.5 In der Rieden, et al. 2010	NF stage 10.5 Hou, et al. 2007	NF stage 10.5 Yelin, et al. 2005	NF stage 10.5 Yasuoka, et al. 2014
NF stage 10.5 Yelin, et al. 2005	NF stage 10.5 Yao, et al. 2001	NF stage 10 to NF stage 10.5 Loreti, et al. 2020	NF stage 9 to NF stage 10.5 Sudou, et al. 2012	NF stage 10.5 Delaune, et al. 2005
NF stage 10.5 Gawantka, et al. 1998	NF stage 10.5 Mukherjee, et al. 2020	NF stage 10.5 Rankin, et al. 2011	NF stage 10.25 to NF stage 10.5 Forecki, et al. 2018	NF stage 10.5 Nagano, et al. 2006
NF stage 10.5 Sudou, et al. 2012	NF stage 10.5 Ossipova, et al. 2005	NF stage 10.5 Zheng, et al. 2015	NF stage 10.5 to NF stage 11 Andreazzoli, et al. 1997	NF stage 11 Kurata, et al. 2003
NF stage 10.5 to NF stage 11 Zhang, et al. 2012	NF stage 11 Kodjabachian, et al. 2001	NF stage 10 to NF stage 11 Kulkarni, et al. 2018	NF stage 11 Hino, et al. 2003	NF stage 11 Louie, et al. 2009
NF stage 11 Gur, et al. 2022	NF stage 11 Shieh, et al. 2014	NF stage 11 Wagner, et al. 2017	NF stage 11 Shinga, et al. 2001	NF stage 11.5 McNulty, et al. 2005
NF stage 10.5 to NF stage 11.5 Gamse, et al. 2001	NF stage 10.5 to NF stage 11.5 Hufton, et al. 2006	NF stage 11.5 Morgan, et al. 2003	NF stage 12 Michaut, et al. 2011	NF stage 10.25 to NF stage 12 Vignali, et al. 2000
NF stage 11.5 to NF stage 12 Monsoro-Burq, et al. 2003	NF stage 12 Borday, et al. 2018	NF stage 12 Borday, et al. 2018	NF stage 12 Li, et al. 2009	NF stage 12.5 Faure, et al. 2005
NF stage 12.5 Rorick, et al. 2007	NF stage 10 to NF stage 12.5 Hiratani, et al. 2003	NF stage 12.5 Tereshina, et al. 2006	NF stage 12.5 Morgan, et al. 1999	NF stage 13 Pitcairn, et al. 2017
NF stage 13 Pierce, et al. 1996	NF stage 13 Tanibe, et al. 2008	NF stage 13 Rorick, et al. 2007	NF stage 13 Parlier, et al. 2013	NF stage 13 Rorick, et al. 2007
NF stage 12 to NF stage 13 Zuber, et al. 2003	NF stage 13 Choi, et al. 2002	NF stage 13 Yamamoto, et al. 2005	NF stage 10.5 to NF stage 13 Habas, et al. 2001	NF stage 10.5 to NF stage 13 Sato, et al. 2006
NF stage 10.5 to NF stage 13 Djiane, et al. 2000	NF stage 12 to NF stage 13 Steventon, et al. 2012	NF stage 13 Acosta, et al. 2015	NF stage 14 Kurata, et al. 2003	NF stage 14 Harata, et al. 2019
NF stage 13 to NF stage 14 Satou, et al. 2018	NF stage 14 Lu, et al. 2015	NF stage 13 to NF stage 14 Greenberg, et al. 2019	NF stage 14 Belyaeva, et al. 2012	NF stage 14 Acosta, et al. 2015
NF stage 14 Furushima, et al. 2007	NF stage 14 Read, et al. 1998	NF stage 14 Ermakova, et al. 2007	NF stage 14 Rorick, et al. 2007	NF stage 14 Cornesse, et al. 2005
NF stage 14 Acosta, et al. 2015	NF stage 14 Glavic, et al. 2002	NF stage 14 Acosta, et al. 2015	NF stage 14 Glavic, et al. 2002	NF stage 14 Khadka, et al. 2009
NF stage 14 Eroshkin, et al. 2016	NF stage 10.5 to NF stage 14 Shibata, et al. 2005	NF stage 14 Rodríguez-Seguel, et al. 2009	NF stage 13 to NF stage 14 Mamada, et al. 2009	NF stage 13 to NF stage 14 Mamada, et al. 2009
NF stage 10.5 to NF stage 14 Liu, et al. 2008	NF stage 14 Yang, et al. 2003	NF stage 14 Xu, et al. 2012	NF stage 14 Senturker, et al. 2012	NF stage 13 to NF stage 14 Gammill, et al. 2000
NF stage 15 Keren-Politansky, et al. 2009	NF stage 11 to NF stage 15 Heeg-Truesdell, et al. 2006	NF stage 13 to NF stage 15 Yan, et al. 2007	NF stage 15 Gammill, et al. 1997	NF stage 13 to NF stage 15 Kazanskaya, et al. 1997
NF stage 11 to NF stage 15 Sudou, et al. 2012	NF stage 15 Murgan, et al. 2014	NF stage 15 Eroshkin, et al. 2016	NF stage 15 Sridharan, et al. 2018	NF stage 15 Vitorino, et al. 2015
NF stage 15 Kazanskaya, et al. 2000	NF stage 15 Tanibe, et al. 2012	NF stage 15 Maczkowiak, et al. 2010	NF stage 15 Reversade, et al. 2005	NF stage 15 Acosta, et al. 2015
NF stage 16 Exner, et al. 2017	NF stage 16 Kurata, et al. 2003	NF stage 16 Tereshina, et al. 2014	NF stage 16 Tereshina, et al. 2014	NF stage 16 Freeman, et al. 2008
NF stage 16 Exner, et al. 2017	NF stage 16 Exner, et al. 2017	NF stage 16 Yang, et al. 2003	NF stage 16 Schuff, et al. 2010	NF stage 16 Min, et al. 2011
NF stage 16 Min, et al. 2011	NF stage 14 to NF stage 16 Koide, et al. 2001	NF stage 17 Li, et al. 2006	NF stage 16 to NF stage 17 Cho, et al. 2017	NF stage 17 Hartley, et al. 2001
NF stage 17 Barreto, et al. 2003	NF stage 17 Min, et al. 2011	NF stage 17 Chang, et al. 2007	NF stage 17 Hikasa, et al. 2010	NF stage 17 Glavic, et al. 2002
NF stage 11.5 to NF stage 17 Lee, et al. 2018	NF stage 17 Pera, et al. 2001	NF stage 17 Papalopulu, et al. 1996	NF stage 17 Pera, et al. 2001	NF stage 17 Polevoy, et al. 2017
NF stage 17 Cho, et al. 2017	NF stage 16 to NF stage 17 Mii, et al. 2009	NF stage 18 Young, et al. 2014	NF stage 16 to NF stage 18 Tanibe, et al. 2008	NF stage 12 to NF stage 18 Zakin, et al. 2005
NF stage 18 Morita, et al. 2013	NF stage 18 Young, et al. 2014	NF stage 18 Luehders, et al. 2015	NF stage 18 Roche, et al. 2009	NF stage 13 to NF stage 18 Glavic, et al. 2002
NF stage 18 Ritter, et al. 2020	NF stage 18 Young, et al. 2014	NF stage 18 Chang, et al. 2020	NF stage 18 Young, et al. 2014	NF stage 18 Fletcher, et al. 2008
NF stage 18 Alexandrova, et al. 2006	NF stage 18 Kurata, et al. 2003	NF stage 18 Wessely, et al. 2005	NF stage 18 Kim, et al. 2011	NF stage 18 Glavic, et al. 2002
NF stage 18 Mercurio, et al. 2004	NF stage 18 Kuo, et al. 1998	NF stage 18 Roche, et al. 2009	NF stage 18 Larraín, et al. 2001	NF stage 18 Satow, et al. 2002
NF stage 14 to NF stage 18 Figueiredo, et al. 2017	NF stage 18 Kim, et al. 2015	NF stage 18 Zuber, et al. 2003	NF stage 18 Young, et al. 2014	NF stage 13 to NF stage 18 Ambrosio, et al. 2008
NF stage 18 to NF stage 19 Wei, et al. 2012	NF stage 19 De Marco, et al. 2011	NF stage 19 Nichane, et al. 2008	NF stage 19 Nichane, et al. 2008	NF stage 19 Hartley, et al. 2001
NF stage 19 Murgan, et al. 2014	NF stage 19 De Marco, et al. 2011	NF stage 19 De Marco, et al. 2011	NF stage 18 to NF stage 19 Murgan, et al. 2014	NF stage 11 to NF stage 20 Hino, et al. 2003
NF stage 20 Wu, et al. 2006	NF stage 20 Kibardin, et al. 2006	NF stage 19 to NF stage 20 Chen, et al. 2001	NF stage 20 Reversade, et al. 2005	NF stage 20 Fletcher, et al. 2006
NF stage 20 Fletcher, et al. 2006	NF stage 12.5 to NF stage 20 Vacik, et al. 2011	NF stage 20 Lloret-Vilaspasa, et al. 2010	NF stage 20 Steventon, et al. 2012	NF stage 20 Wacker, et al. 2004
NF stage 18 to NF stage 20 Rasmussen, et al. 2001	NF stage 20 Nicetto, et al. 2013	NF stage 20 Belyaeva, et al. 2012	NF stage 20 Borchers, et al. 2002	NF stage 20 Ding, et al. 2017
NF stage 20 Popov, et al. 2017	NF stage 20 Lamb, et al. 1995	NF stage 20 Lamb, et al. 1995	NF stage 19 to NF stage 20 Jin, et al. 2018	NF stage 15 to NF stage 21 Ogino, et al. 2008
NF stage 13 to NF stage 21 Suzuki, et al. 2000	NF stage 19 to NF stage 21 Borchers, et al. 2002	NF stage 21 Dibner, et al. 2001	NF stage 21 Galli, et al. 2003	NF stage 21 Sater, et al. 2003
NF stage 13 to NF stage 21 Dupont, et al. 2009	NF stage 21 Rauschenberger, et al. 2017	NF stage 13 to NF stage 21 Jalvy, et al. 2019	NF stage 13 to NF stage 21 Hatch, et al. 2016	NF stage 22 Wills, et al. 2010
NF stage 22 Lee, et al. 2006	NF stage 22 Pai, et al. 2012	NF stage 22 McNulty, et al. 2005	NF stage 18 to NF stage 22 Luehders, et al. 2015	NF stage 22 Kim, et al. 2005
NF stage 22 Eivers, et al. 2009	NF stage 14 to NF stage 22 Vignali, et al. 2000	NF stage 22 Lupo, et al. 2002	NF stage 22 Escalante-Alcalde, et al. 2003	NF stage 10 to NF stage 22 Szenker, et al. 2012
NF stage 23 Inomata, et al. 2008	NF stage 23 Flach, et al. 2018	NF stage 23 Kiem, et al. 2017	NF stage 23 Bugner, et al. 2011	NF stage 13 to NF stage 23 Seigfried, et al. 2017
NF stage 24 Zhu, et al. 2017	NF stage 24 De Marco, et al. 2011	NF stage 22 to NF stage 24 Reversade, et al. 2005	NF stage 22 to NF stage 24 Silva, et al. 2003	NF stage 24 Vignali, et al. 2000
NF stage 24 Inomata, et al. 2013	NF stage 15 to NF stage 24 Fish, et al. 2014	NF stage 12.5 to NF stage 24 Zheng, et al. 2015	NF stage 23 to NF stage 24 Park, et al. 2008	NF stage 24 Inomata, et al. 2013
NF stage 24 Takebayashi-Suzuki, et al. 2011	NF stage 25 Oelgeschläger, et al. 2003	NF stage 25 Pai, et al. 2018	NF stage 25 Schuff, et al. 2010	NF stage 25 Pai, et al. 2020
NF stage 25 Lee, et al. 2005	NF stage 24 to NF stage 25 Zhu, et al. 2017	NF stage 25 Zoltewicz, et al. 1997	NF stage 26 Iglesias, et al. 2008	NF stage 26 Herrera-Úbeda, et al. 2019
NF stage 25 to NF stage 26 Wills, et al. 2006	NF stage 19 to NF stage 26 Yoshitake, et al. 1999	NF stage 26 Ishibashi, et al. 2008	NF stage 26 Komiya, et al. 2014	NF stage 26 Sudou, et al. 2012
NF stage 28 Chang, et al. 2007	NF stage 28 Macrì, et al. 2013	NF stage 14 to NF stage 28 Lunardi, et al. 2006	NF stage 28 Shi, et al. 1998	NF stage 27 to NF stage 28 Murgan, et al. 2014
NF stage 14 to NF stage 28 Rasmussen, et al. 2001	NF stage 27 to NF stage 28 Murgan, et al. 2014	NF stage 28 Lutz, et al. 1999	NF stage 11.5 to NF stage 28 Yamamoto, et al. 2005	NF stage 28 Ryan, et al. 1998
NF stage 28 Ermakova, et al. 2007	NF stage 17 to NF stage 28 Zhang, et al. 2014	NF stage 28 Guiral, et al. 2010	NF stage 28 Neilson, et al. 2017	NF stage 28 Neilson, et al. 2017
NF stage 28 Yao, et al. 2001	NF stage 19 to NF stage 28 Adams, et al. 2016	NF stage 28 Macrì, et al. 2013	NF stage 28 Macrì, et al. 2013	NF stage 29 and 30 Kunz, et al. 2004
NF stage 29 and 30 Gawantka, et al. 1998	NF stage 29 and 30 Lai, et al. 1995	NF stage 29 and 30 Pai, et al. 2012	NF stage 17 to NF stage 29 and 30 Vacca, et al. 2016	NF stage 29 and 30 Yamaguti, et al. 2005
NF stage 17 to NF stage 29 and 30 Vacca, et al. 2016	NF stage 29 and 30 Juraver-Geslin, et al. 2014	NF stage 29 and 30 Kunz, et al. 2004	NF stage 20 to NF stage 31 Viczian, et al. 2003	NF stage 19 to NF stage 31 Kreis, et al. 2020
NF stage 32 Juraver-Geslin, et al. 2014	NF stage 32 Juraver-Geslin, et al. 2014	NF stage 32 LeSueur, et al. 2002	NF stage 32 Cizelsky, et al. 2013	NF stage 28 to NF stage 32 Shah, et al. 2020
NF stage 32 Schaefer, et al. 1999	NF stage 32 Fredieu, et al. 1997	NF stage 32 Fredieu, et al. 1997	NF stage 32 Wagner, et al. 2017	NF stage 32 Thomas, et al. 2009
NF stage 14 to NF stage 32 Henry, et al. 2002	NF stage 13 to NF stage 33 and 34 Qiu, et al. 2009	NF stage 33 and 34 Vitorino, et al. 2015	NF stage 33 and 34 Nothias, et al. 1998	NF stage 35 and 36 Saint-Germain, et al. 2004
NF stage 35 and 36 Park, et al. 2009	NF stage 13 to NF stage 35 and 36 Lallier, et al. 2000	NF stage 35 and 36 Park, et al. 2010	NF stage 35 and 36 Elkins, et al. 2006	NF stage 35 and 36 Rauschenberger, et al. 2010
NF stage 15 to NF stage 35 and 36 Zhang, et al. 2014	NF stage 35 and 36 Saint-Germain, et al. 2004	NF stage 40 Decembrini, et al. 2006	NF stage 40 Atkinson-Leadbeater, et al. 2014	NF stage 40 Tae, et al. 2015
NF stage 40 Perron, et al. 1998	NF stage 41 Viczian, et al. 2003	NF stage 41 Viczian, et al. 2003	NF stage 41 Viczian, et al. 2003	NF stage 25 to NF stage 41 Viczian, et al. 2003
NF stage 32 to NF stage 41 Wang, et al. 2005	NF stage 42 Decembrini, et al. 2006	NF stage 42 Decembrini, et al. 2008	NF stage 35 and 36 to NF stage 42 De Marco, et al. 2011	NF stage 33 and 34 to NF stage 42 Decembrini, et al. 2006
NF stage 33 and 34 to NF stage 42 Decembrini, et al. 2008	NF stage 22 to NF stage 44 Dale, et al. 2002	NF stage 10.25 to NF stage 44 Blitz, et al. 2003	NF stage 27 to NF stage 45 Bocquet, et al. 2023	NF stage 42 to NF stage 45 Decembrini, et al. 2008
NF stage 45 Lunardi, et al. 2006	NF stage 40 to NF stage 48 Bou-Rouphael, et al. 2024	NF stage 54 Casarosa, et al. 2005	NF stage 63 Casarosa, et al. 2005	NF stage 45 to NF stage 66 Kriebitz, et al. 2009
NF stage 10.5 to NF stage 66 Bell, et al. 2003