il12b Phenotypes

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Phenotypes

Gene Literature (16)

Nucleotides (17)

Interactants (92)

XB-GENEPAGE-480286

Gene Symbol: il12b Gene Name: interleukin 12B

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: il12b assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (1 source): Immunodeficiency
Mouse (15 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal CD8-positive, alpha-beta T cell physiology, abnormal T-helper 1 physiology, abnormal granulocyte physiology, abnormal lymphocyte physiology, abnormal macrophage physiology, decreased circulating interferon-gamma level, decreased incidence of tumors by chemical induction, decreased interferon-gamma secretion, decreased interleukin-17 secretion, decreased susceptibility to type IV hypersensitivity reaction, impaired natural killer cell mediated cytotoxicity, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to parasitic infection [+]
View all ortholog results at Monarch