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XB-GENEPAGE-5918040
pklr pyruvate kinase L/R
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Computed annotations: pklr assayed (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (24 sources): Abnormal erythrocyte morphology, Abnormality of the amniotic fluid, Anemia, Anisocytosis, Cholecystitis, Cholelithiasis, Chronic hemolytic anemia, Congenital hemolytic anemia, Elevated transferrin saturation, Hydrops fetalis, [+] |
Mouse (14 sources): abnormal common myeloid progenitor cell morphology, abnormal erythropoiesis, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, decreased susceptibility to parasitic infection, decreased susceptibility to parasitic infection induced morbidity/mortality, hemosiderosis, increased erythroblast number, increased erythrocyte clearance, [+] |
View all ortholog results at Monarch |