traf3ip2 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (40)

Interactants (12)

XB-GENEPAGE-6035450

Gene Symbol: traf3ip2 Gene Name: TRAF3 interacting protein 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: traf3ip2 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (31 sources): Abnormal dental enamel morphology, Abnormal endocardium morphology, Abnormal fingernail morphology, Abnormal lip morphology, Abnormal toenail morphology, Abnormal vagina morphology, Abnormality of temperature regulation, Abnormality of the immune system, Abnormality of the mouth, Abnormality of the nail, Abnormality of the orbital region, Abnormality of the skin, Abnormality of vision, Broad nail, Cheilitis, Cough, Dyspareunia, Erythema, Feeding difficulties in infancy, Hematuria, Hemoptysis, Hepatitis, Hyperkeratosis, Papule, Pruritus, Recurrent infections, Recurrent respiratory infections, Recurrent urinary tract infections, Seizure, Skin rash, Skin ulcer [+]
Mouse (40 sources): abnormal exocrine gland morphology, abnormal glomerular capillary morphology, abnormal renal glomerulus morphology, abnormal spleen B cell corona morphology, abnormal transitional stage B cell morphology, decreased interleukin-6 secretion, decreased susceptibility to autoimmune disorder, dermatitis, dry eyes, enlarged cervical lymph nodes, enlarged lymph nodes, enlarged submandibular lymph nodes, immune system phenotype, impaired eosinophil recruitment, impaired macrophage chemotaxis, impaired neutrophil recruitment, increased IgG1 level, increased IgG2c level, increased anti-chromatin antibody level, increased anti-double stranded DNA antibody level, increased anti-histone antibody level, increased anti-nuclear antigen antibody level, increased anti-single stranded DNA antibody level, increased autoantibody level, increased dendritic cell number, increased follicular B cell number, increased immature B cell number, increased marginal zone B cell number, increased mesangial cell number, increased pruritus, increased spleen weight, increased submandibular gland size, increased transitional stage B cell number, lacrimal gland inflammation, lymphoid hyperplasia, premature death, renal glomerular immunoglobulin deposits, respiratory system inflammation, spleen hyperplasia, submandibular gland inflammation [+]
View all ortholog results at Monarch