| Monarch Ortholog Phenotypes
|
Human (34 sources):
Abnormal cardiac septum morphology,
Abnormal localization of kidney,
Abnormal nasal morphology,
Abnormally large globe,
Atrial septal defect,
Axial hypotonia,
Blindness,
Depressed nasal bridge,
Frontal bossing,
Global developmental delay,
High forehead,
Hydrocephalus,
Hypertelorism,
Hypoplasia of the corpus callosum,
Intellectual disability, profound,
Knee flexion contracture,
Kyphosis,
Long palpebral fissure,
Macrocephaly,
Megalencephaly,
Mitral regurgitation,
Narrow mouth,
Pachygyria,
Polymicrogyria,
Postaxial hand polydactyly,
Postaxial polydactyly,
Ptosis,
Seizure,
Skeletal muscle atrophy,
Telecanthus,
Thick corpus callosum,
Thoracic scoliosis,
Vascular ring,
Ventricular septal defect
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Mouse (2 sources):
decreased circulating glucose level,
increased insulin sensitivity
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.