| Monarch Ortholog Phenotypes
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Human (25 sources):
Abnormal bleeding,
Abnormal mitral valve morphology,
Abnormal platelet function,
Abnormality of coagulation,
Abnormality of the genitourinary system,
Abnormality of thrombocytes,
Aortic valve stenosis,
Bruising susceptibility,
Deviation of finger,
Epistaxis,
Gastrointestinal angiodysplasia,
Gastrointestinal hemorrhage,
Impaired platelet aggregation,
Ischemic stroke,
Joint hemorrhage,
Menorrhagia,
Mitral valve prolapse,
Persistent bleeding after trauma,
Prolonged bleeding after surgery,
Prolonged bleeding time,
Prolonged whole-blood clotting time,
Reduced factor VIII activity,
Reduced von Willebrand factor activity,
Thrombocytopenia,
Venous insufficiency
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Mouse (12 sources):
abnormal blood coagulation,
abnormal blood-brain barrier function,
abnormal platelet activation,
abnormal response to injury,
decreased myocardial infarct size,
decreased susceptibility to induced thrombosis,
decreased susceptibility to ischemic brain injury,
homeostasis/metabolism phenotype,
impaired blood coagulation,
increased acute inflammation,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.