Monarch Ortholog Phenotypes
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Human (16 sources):
Abnormality of the hypothalamus-pituitary axis,
Adrenal hypoplasia,
Cryptorchidism,
Delayed puberty,
Diabetes insipidus,
Ectopic posterior pituitary,
Failure to thrive,
Global developmental delay,
Hypoglycemia,
Hypoplasia of penis,
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Mouse (31 sources):
abnormal axon extension,
abnormal axon guidance,
abnormal bone mineralization,
abnormal brain commissure morphology,
abnormal bronchiole morphology,
abnormal bronchus morphology,
abnormal embryonic/fetal subventricular zone morphology,
abnormal freezing behavior,
abnormal hippocampal commissure morphology,
abnormal kidney morphology,
abnormal limb morphology,
abnormal lung development,
abnormal mammary gland duct morphology,
abnormal neurite morphology,
abnormal olfactory tract morphology,
abnormal pulmonary alveolus morphology,
abnormal pulmonary interalveolar septum morphology,
abnormal sex gland morphology,
abnormal spinal cord lateral column morphology,
aphagia,
bronchial epithelial hyperplasia,
decreased bone mineral content,
decreased corpus callosum size,
decreased freezing behavior,
decreased hippocampal commissure size,
increased lymphoma incidence,
increased mammary gland epithelial cell proliferation,
neonatal lethality, incomplete penetrance,
perinatal lethality, complete penetrance,
preweaning lethality, incomplete penetrance,
thick pulmonary interalveolar septum
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View all ortholog results at Monarch
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