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XB-GENEPAGE-953398
smcr8 Smith-Magenis syndrome chromosome region, candidate 8
Monarch Ortholog Phenotypes
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Mouse (10 sources): abnormal autophagy, abnormal lysosome morphology, abnormal protein level, enlarged lymph nodes, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased circulating interleukin-12b level, increased interleukin-6 secretion, increased susceptibility to induced colitis, increased tumor necrosis factor secretion |