Monarch Ortholog Phenotypes
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Mouse (34 sources):
abnormal bone mineralization,
abnormal brain weight,
abnormal dendritic mushroom spine morphology,
abnormal dendritic spine morphology,
abnormal direction of heart looping,
abnormal grip strength,
abnormal hippocampus neuron morphology,
abnormal lean body mass,
abnormal left-right axis patterning,
abnormal response to novel object,
abnormal social investigation,
absent embryonic cilia,
decreased corpus callosum size,
decreased embryo size,
decreased lean body mass,
decreased prepulse inhibition,
decreased red blood cell distribution width,
decreased thigmotaxis,
distended pericardium,
embryonic lethality during organogenesis, complete penetrance,
enhanced long term potentiation,
impaired spatial learning,
impaired synaptic plasticity,
incomplete embryo turning,
increased bone mineral content,
increased grip strength,
increased grooming behavior,
increased lean body mass,
open neural tube,
prenatal lethality prior to heart atrial septation,
preweaning lethality, complete penetrance,
reduced NMDA-mediated synaptic currents,
reduced long term depression,
thin hippocampus stratum radiatum
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