Monarch Ortholog Phenotypes
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Mouse (25 sources):
abnormal common lymphocyte progenitor cell morphology,
abnormal embryo size,
abnormal forebrain development,
abnormal hematopoietic cell number,
abnormal hindbrain development,
abnormal inner cell mass morphology,
abnormal midbrain development,
abnormal myelopoiesis,
decreased bone marrow cell number,
decreased common myeloid progenitor cell number,
decreased erythrocyte cell number,
decreased hematopoietic stem cell number,
decreased hematopoietic stem cell proliferation,
decreased splenocyte number,
embryonic lethality between implantation and somite formation, complete penetrance,
embryonic lethality between somite formation and embryo turning, complete penetrance,
embryonic lethality prior to organogenesis,
embryonic lethality prior to tooth bud stage,
increased bone marrow cell number,
increased granulocyte number,
increased neutrophil cell number,
increased number of Howell-Jolly bodies,
myeloid hyperplasia,
no abnormal phenotype detected,
preweaning lethality, complete penetrance
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