| Monarch Ortholog Phenotypes
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Human (11 sources):
Abnormal cardiovascular system physiology,
Abnormal joint morphology,
Abnormality of the vasculature,
Abnormality of the vertebral column,
Arterial calcification,
Arterial occlusion,
Arterial tortuosity,
Coronary artery calcification,
Decreased serum creatinine,
Ectopic ossification,
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Mouse (12 sources):
abnormal renal vascular resistance,
abnormal response to cardiac infarction,
abnormal response/metabolism to endogenous compounds,
abnormal snout skin morphology,
calcified skin,
decreased bleeding time,
decreased coronary flow rate,
increased aggression towards humans,
increased circulating alkaline phosphatase level,
increased myocardial infarct size,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.