pold1 Phenotypes

Phenotypes

XB-GENEPAGE-1002130

Gene Symbol: pold1 Gene Name: polymerase (DNA directed), delta 1, catalytic subunit

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (32 sources): Abnormally high-pitched voice, Adenocarcinoma of the colon, Adenomatous colonic polyposis, Brain neoplasm, Breast carcinoma, Carcinoma, Colorectal polyposis, Convex nasal ridge, Cryptorchidism, Dental crowding, Dermal atrophy, Diabetes mellitus, Elevated circulating hepatic transaminase concentration, Endometrial carcinoma, Flexion contracture, Hepatic steatosis, Hepatomegaly, Hypertriglyceridemia, Hypogonadism, Insulin resistance, Kyphosis, Lack of skin elasticity, Lipodystrophy, Micrognathia, Narrow mouth, Neoplasm of the rectum, Osteoporosis, Proptosis, Scleroderma, Scoliosis, Sensorineural hearing impairment, Telangiectasia [+]
Mouse (15 sources): abnormal trophoblast layer morphology, absent inner cell mass proliferation, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality between somite formation and embryo turning, complete penetrance, embryonic lethality during organogenesis, complete penetrance, embryo phenotype, enlarged thymus, increased intestinal adenoma incidence, increased lung tumor incidence, increased lymphoma incidence, increased skin tumor incidence, increased T cell derived lymphoma incidence, increased tumor incidence, inner cell mass degeneration, premature death [+]
View all ortholog results at Monarch