Dermal atrophy, Emphysema, Epiphyseal stippling, Global developmental delay, Growth abnormality, Hearing impairment, Hypertension, Intellectual disability, mild, Long face, Macrotia, Malar flattening, Midface retrusion, Miscarriage, Nasal speech, Optic atrophy, Peripheral pulmonary artery stenosis, Premature fusion of phalangeal epiphyses, Pulmonary arterial hypertension, Pulmonary artery hypoplasia, Pulmonary artery stenosis, Pulmonic stenosis, Recurrent bronchitis, Recurrent otitis media, Recurrent respiratory infections, Recurrent sinusitis, Seizure, Short distal phalanx of finger, Short hallux, Short stature, Short thumb, Sinusitis, Sloping forehead, Soft, doughy skin, Tracheal atresia, Underdeveloped nasal alae, Ventricular septal defect, Wide nose, obsolete Hypotrichosis

abnormal long bone epiphyseal plate proliferative zone, abnormal lung vasculature morphology, abnormal osteoblast physiology, abnormal renal glomerulus morphology, abnormal tracheal cartilage morphology, decreased body size, decreased bone mass, decreased bone ossification, decreased bone trabecula number, decreased bone volume, decreased compact bone mass, decreased trabecular bone mass, decreased trabecular bone thickness, decreased width of hypertrophic chondrocyte zone, increased circulating osteocalcin level, increased kidney weight, premature death, slow postnatal weight gain, small kidney, small lung