tnfaip8l2 Phenotypes

Phenotypes

XB-GENEPAGE-1005114

Gene Symbol: tnfaip8l2 Gene Name: TNF alpha induced protein 8 like 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tnfaip8l2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (26 sources): abnormal B cell activation, abnormal CD4-positive, alpha-beta T cell physiology, abnormal T cell apoptosis, abnormal cytotoxic T cell physiology, abnormal macrophage activation involved in immune response, abnormal myeloid dendritic cell morphology, chronic inflammation, decreased IgG2a level, decreased IgG2b level, decreased survivor rate, increased circulating interleukin-1 beta level, increased circulating interleukin-10 level, increased circulating interleukin-12 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased interferon-gamma secretion, increased interleukin-1 beta secretion, increased interleukin-12 secretion, increased interleukin-17 secretion, increased interleukin-2 secretion, increased interleukin-4 secretion, increased interleukin-6 secretion, increased spleen white pulp amount, increased susceptibility to endotoxin shock, increased tumor necrosis factor secretion, spleen hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (26 sources): abnormal B cell activation, abnormal CD4-positive, alpha-beta T cell physiology, abnormal T cell apoptosis, abnormal cytotoxic T cell physiology, abnormal macrophage activation involved in immune response, abnormal myeloid dendritic cell morphology, chronic inflammation, decreased IgG2a level, decreased IgG2b level, decreased survivor rate, [+]