pck1 Phenotypes

Phenotypes

XB-GENEPAGE-1009229

Gene Symbol: pck1 Gene Name: phosphoenolpyruvate carboxykinase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: pck1 assayed (1 source)
Computed annotations: pck1 assayed (6 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal brown fat cell morphology, abnormal circulating lipid level, abnormal postnatal growth, abnormal white adipose tissue physiology, abnormal white fat cell morphology, absent gastric milk in neonates, decreased abdominal adipose tissue amount, decreased body size, decreased brown fat cell number, decreased brown fat cell size, decreased circulating glucose level, decreased circulating ketone body level, decreased epididymal fat pad weight, decreased liver glycogen level, decreased liver triglyceride level, decreased percent body fat/body weight, decreased white adipose tissue amount, decreased white fat cell lipid droplet size, decreased white fat cell size, homeostasis/metabolism phenotype, increased circulating ketone body level, increased circulating lactate level, increased liver triglyceride level, increased liver weight, no abnormal phenotype detected, pale liver, postnatal lethality, complete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal brown fat cell morphology, abnormal circulating lipid level, abnormal postnatal growth, abnormal white adipose tissue physiology, abnormal white fat cell morphology, absent gastric milk in neonates, decreased abdominal adipose tissue amount, decreased body size, decreased brown fat cell number, decreased brown fat cell size, [+]