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XB-GENEPAGE-1009710
nup205 nucleoporin 205kDa
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal multiciliated cell (3 sources), abnormally localised basal body (2 sources), abnormal multiciliated epidermal cell (2 sources), abnormal heart looping (1 source), abnormally decreased number of cilium in the floor plate (1 source), abnormally decreased number of cilium in the mucociliary epithelium (1 source), absent cilium (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: nup205 manipulated (3 sources) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| ciliopathy (4AP sources, 1 EP source), congenital heart disease (2AP sources, 1 EP source) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xtr wt+ nup205 MO (7 sources), Xtr wt + nup188 MO + nup205 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (4 sources): decreased body length, decreased lean body mass, increased total body fat amount, preweaning lethality, complete penetrance |