dab1 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (171)

Interactants (61)

XB-GENEPAGE-1010387

Gene Symbol: dab1 Gene Name: Dab, reelin signal transducer, homolog 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dab1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (24 sources): Abnormal conjugate eye movement, Ataxia, Cerebellar atrophy, Cerebellar vermis atrophy, Cogwheel rigidity, Diffuse cerebellar atrophy, Dysarthria, Dysdiadochokinesis, Dysphagia, Falls, Frequent falls, Gait disturbance, Horizontal nystagmus, Ischemic stroke, Limb dysmetria, Myoclonus, Neurological speech impairment, Nystagmus, Scanning speech, Sensorineural hearing impairment, Somatic sensory dysfunction, Tremor, Truncal ataxia, Unsteady gait [+]
Mouse (45 sources): abnormal bone marrow morphology, abnormal cerebellar Purkinje cell layer, abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal cerebellar layer morphology, abnormal cerebral cortex morphology, abnormal cone electrophysiology, abnormal cortical marginal zone morphology, abnormal dentate gyrus morphology, abnormal hippocampus CA2 region morphology, abnormal hippocampus layer morphology, abnormal hippocampus pyramidal cell layer, abnormal hippocampus pyramidal cell morphology, abnormal neocortex morphology, abnormal neuronal precursor cell migration, abnormal olfactory bulb granule cell layer morphology, abnormal postnatal subventricular zone morphology, abnormal retina inner nuclear layer morphology, abnormal retina rod bipolar cell morphology, abnormal rod electrophysiology, abnormal rostral migratory stream morphology, abnormal stratification in cerebral cortex, abnormal subplate morphology, abnormal tail movements, abnormal telencephalon development, absent cerebellar foliation, absent subplate, behavior/neurological phenotype, decreased body size, decreased survivor rate, ectopic Purkinje cell, impaired balance, impaired righting response, lethality at weaning, complete penetrance, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, prenatal lethality, incomplete penetrance, small cerebellum, thin body, thymus atrophy, weakness [+]
View all ortholog results at Monarch