| Monarch Ortholog Phenotypes
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Human (4 sources):
Reticular pigmentary degeneration,
Retinal dystrophy,
Varicose veins,
Visual impairment
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Mouse (24 sources):
abnormal Bruch membrane morphology,
abnormal body wall morphology,
abnormal cecum morphology,
abnormal choriocapillaris morphology,
abnormal coat appearance,
abnormal cutaneous elastic fiber morphology,
abnormal retina pigment epithelium morphology,
abnormal uterus morphology,
abnormal xiphoid process morphology,
decreased body size,
decreased kidney weight,
decreased litter size,
decreased liver weight,
decreased skeletal muscle weight,
decreased spleen weight,
herniated intestine,
homeostasis/metabolism phenotype,
no abnormal phenotype detected,
premature aging,
premature death,
premature hair loss,
reduced fertility,
retina pigment epithelium atrophy,
vision/eye phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.