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XB-GENEPAGE-1012565
fermt2 FERM domain containing kindlin 2
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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decreased size of the Meckel's cartilage (2 sources), decreased size of the ceratobranchial I (2 sources), decreased size of the ceratobranchial II (2 sources), decreased size of the ceratobranchial III (2 sources), decreased size of the ceratobranchial IV (2 sources), decreased size of the ceratohyal (2 sources), decreased size of the chondrocranium (2 sources), abnormal cell migration in neural crest (1 source), abnormal development of cardiovascular system (1 source), abnormal development of heart (1 source), abnormal migratory neural crest cell (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: fermt2 manipulated (19 sources) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + fermt2 MO (9 sources), Xla Wt + fermt2 MO (7 sources), Xla Wt + chd1 + fermt2 MO + animal cap explant (1 source), Xla Wt + fermt2 (1 source), Xla Wt + fermt2Q614A_W615A-myc (1 source), Xla Wt + wnt3a + fermt2 MO + animal cap explant (1 source), Xtr Wt + fermt2 CRISPR (1 source), Xtr Wt + fermt2 MO (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Mouse (32 sources): abnormal cell adhesion, abnormal chondrocyte morphology, abnormal embryonic epiblast morphology, abnormal germ layer development, abnormal limb development, abnormal long bone epiphyseal plate morphology, abnormal long bone epiphyseal plate proliferative zone, abnormal long bone hypertrophic chondrocyte zone, abnormal sternum morphology, absent neurocranium, [+] |