| Monarch Ortholog Phenotypes
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Human (16 sources):
Abnormality of the dentition,
Abnormality of the gingiva,
Acral ulceration,
Anhidrosis,
Decreased number of small peripheral myelinated nerve fibers,
Deeply set eye,
Impaired pain sensation,
Impaired temperature sensation,
Intellectual disability, mild,
Malar flattening,
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Mouse (30 sources):
abnormal cholinergic neuron morphology,
abnormal dorsal root ganglion morphology,
abnormal innervation,
abnormal myocardial fiber morphology,
abnormal myocardium layer morphology,
abnormal object recognition memory,
abnormal pain threshold,
abnormal pericyte morphology,
abnormal sensory neuron innervation pattern,
abnormal sympathetic ganglion morphology,
abnormal vascular endothelial cell morphology,
abnormal vascular endothelial cell physiology,
absent superior cervical ganglion,
decreased body size,
decreased cardiac muscle contractility,
delayed eyelid opening,
dilated heart left ventricle,
dorsal root ganglion hypoplasia,
hypoalgesia,
impaired spatial learning,
increased vascular permeability,
nervous system phenotype,
no abnormal phenotype detected,
postnatal lethality, incomplete penetrance,
premature death,
slow postnatal weight gain,
small superior cervical ganglion,
superior cervical ganglion hypertrophy,
thin myocardium,
trigeminal ganglion hypertrophy
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.