abnormal level of surface class II molecules, abnormal macrophage physiology, abnormal maxilla morphology, abnormal microglial cell physiology, abnormal myelopoiesis, abnormal proerythroblast morphology, abnormal spleen B cell follicle morphology, abnormal spleen weight, decreased B cell proliferation, decreased B-1 B cell number, decreased bone mineral content, decreased circulating bilirubin level, decreased follicular B cell number, decreased hemoglobin content, decreased large unstained cell number, decreased marginal zone B cell number, decreased mature B cell number, decreased spleen red pulp amount, decreased spleen weight, decreased spleen white pulp amount, decreased transitional stage B cell number, enlarged lymph nodes, impaired hematopoiesis, impaired humoral immune response, increased B cell proliferation, increased B-1 B cell number, increased IgG1 level, increased IgG2b level, increased activated T cell number, increased anti-double stranded DNA antibody level, increased anti-nuclear antigen antibody level, increased autoantibody level, increased circulating interferon-gamma level, increased circulating interleukin-1 beta level, increased circulating interleukin-12 level, increased circulating interleukin-17 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased dendritic cell number, increased granulocyte number, increased immature B cell number, increased macrophage cell number, increased neutrophil cell number, increased plasma cell number, increased red blood cell distribution width, increased spleen weight, increased spleen white pulp amount, increased susceptibility to systemic lupus erythematosus, mesangial cell interposition, myeloid hyperplasia, premature death, renal glomerular immunoglobulin deposits, renal glomerular protein deposits, renal glomerulus hypertrophy, skin lesions, small Peyer's patches, small thymus, spleen hyperplasia