| Monarch Ortholog Phenotypes
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Human (17 sources):
Abnormality of metabolism/homeostasis,
Agenesis of corpus callosum,
Akinesia,
Cerebellar hypoplasia,
Dandy-Walker malformation,
Flexion contracture,
Global developmental delay,
Hydranencephaly,
Hydrocephalus,
Hypoplasia of the brainstem,
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Mouse (23 sources):
abnormal Mullerian duct topology,
abnormal Wolffian duct morphology,
abnormal brain vasculature morphology,
abnormal ductus venosus valve morphology,
abnormal hypoglossal nerve topology,
abnormal pericyte morphology,
abnormal vascular development,
abnormal vascular endothelial cell morphology,
absent ductus venosus valve,
absent segment of posterior cerebral artery,
blood in lymph vessels,
brain ischemia,
brain vascular congestion,
cardiovascular system phenotype,
decreased angiogenesis,
decreased endothelial cell proliferation,
dual inferior vena cava,
embryo tumor,
hepatic portal vein stenosis,
hypoxia,
neonatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
thin hypoglossal nerve
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.