Monarch Ortholog Phenotypes
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Human (53 sources):
Abnormal bleeding,
Abnormal cerebral vascular morphology,
Abnormal megakaryocyte morphology,
Abnormal platelet morphology,
Abnormal thrombosis,
Abnormality of blood and blood-forming tissues,
Abnormality of bone marrow cell morphology,
Abnormality of the skeletal system,
Abnormality of thrombocytes,
Acrocyanosis,
Acute leukemia,
Amaurosis fugax,
Anemia,
Anorexia,
Arterial thrombosis,
Bone marrow hypercellularity,
Cachexia,
Chest pain,
Constitutional symptom,
Easy fatigability,
Ecchymosis,
Extramedullary hematopoiesis,
Fatigue,
Fever,
Flank pain,
Hemangioma,
Hematological neoplasm,
Hepatomegaly,
Hepatosplenomegaly,
Hypertension,
Impaired platelet aggregation,
Increased circulating lactate dehydrogenase concentration,
Increased megakaryocyte count,
Leukocytosis,
Low-grade fever,
Lymphadenopathy,
Myelodysplasia,
Myelofibrosis,
Myeloproliferative disorder,
Myocardial infarction,
Pallor,
Pancytopenia,
Paresthesia,
Petechiae,
Poikilocytosis,
Portal hypertension,
Prolonged bleeding time,
Purpura,
Splenomegaly,
Thrombocytopenia,
Thrombocytosis,
Transient ischemic attack,
Venous thrombosis
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Mouse (27 sources):
abnormal P wave,
abnormal T wave,
abnormal Z line morphology,
abnormal calcium ion homeostasis,
abnormal cell adhesion,
abnormal cell migration,
abnormal heart echocardiography feature,
abnormal intercalated disk morphology,
abnormal interventricular septum muscular part morphology,
abnormal myocardial fiber morphology,
abnormal sarcomere morphology,
cardiac interstitial fibrosis,
decreased QRS amplitude,
decreased cardiac muscle contractility,
decreased myocardial fiber number,
dilated heart left ventricle,
failure of ventral body wall closure,
incomplete rostral neuropore closure,
increased cardiac muscle glycogen level,
increased cardiomyocyte apoptosis,
lethality throughout fetal growth and development, complete penetrance,
lethality throughout fetal growth and development, incomplete penetrance,
small heart,
thin myocardium compact layer,
thin ventricular wall,
trabecula carnea hypoplasia,
ventricular cardiomyopathy
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View all ortholog results at Monarch
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