Hemangioma, Holoprosencephaly, Hypoplasia of penis, Hypotelorism, Hypothyroidism, Intellectual disability, Intrauterine growth retardation, Iris coloboma, Maternal diabetes, Microcephaly, Midnasal stenosis, Narrow nasal bridge, Orofacial cleft, Panhypopituitarism, Premature birth, Renal agenesis, Scoliosis, Seizure, Short nose, Short philtrum, Short stature, Solitary median maxillary central incisor, Strabismus, Tented upper lip vermilion, Tetralogy of Fallot

abnormal heart looping, abnormal left-right axis patterning, abnormal left-right axis symmetry of the somites, abnormal limb morphology, abnormal nasal pit morphology, abnormal nasopharynx morphology, abnormal neural fold formation, abnormal neural plate morphology, abnormal neurocranium morphology, abnormal neuron differentiation, abnormal neuron specification, abnormal occipital bone morphology, abnormal optic vesicle formation, abnormal sclerotome morphology, abnormal somite development, abnormal vascular development, abnormal viscerocranium morphology, abnormal vomeronasal organ morphology, absent basisphenoid bone, absent floor plate, absent occipital bone, absent parietal bone, absent primary palate, absent upper incisors, absent vomeronasal organ, decreased embryo size, delayed chondrocyte differentiation, distended pericardium, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, failure of heart looping, fused first pharyngeal arch, incomplete embryo turning, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, pericardial edema