tox Phenotypes

Phenotypes

XB-GENEPAGE-1019589

Gene Symbol: tox Gene Name: thymocyte selection associated high mobility group box

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tox assayed (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal CD4-positive T cell differentiation, abnormal CD8-positive, alpha beta T cell morphology, abnormal bone mineralization, abnormal circulating alkaline phosphatase level, abnormal positive T cell selection, abnormal startle reflex, absent axillary lymph nodes, absent inguinal lymph nodes, absent mesenteric lymph nodes, absent popliteal lymph nodes, decreased CD4-positive, alpha beta T cell number, decreased NK T cell number, decreased Peyer's patch number, decreased bone mineral content, decreased cytotoxic T cell cytolysis, decreased prepulse inhibition, decreased startle reflex, increased circulating alkaline phosphatase level, small Peyer's patches [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal CD4-positive T cell differentiation, abnormal CD8-positive, alpha beta T cell morphology, abnormal bone mineralization, abnormal circulating alkaline phosphatase level, abnormal positive T cell selection, abnormal startle reflex, absent axillary lymph nodes, absent inguinal lymph nodes, absent mesenteric lymph nodes, absent popliteal lymph nodes, [+]