lin28b Phenotypes

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Phenotypes

XB-GENEPAGE-1218968

Gene Symbol: lin28b Gene Name: lin-28 homolog B

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (1 source): Cognitive impairment
Mouse (34 sources): abnormal cytokine level, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, abnormal jejunum crypts of Lieberkuhn morphology, abnormal sleep behavior, abnormal small intestine crypts of Lieberkuhn morphology, abnormal T cell differentiation, abnormal thymus cell ratio, abnormal thymus cortex morphology, abnormal thymus corticomedullary boundary morphology, decreased body size, decreased CD4-positive, alpha beta T cell number, decreased double-positive T cell number, decreased locomotor activity, decreased Paneth cell number, decreased thymocyte number, digestive/alimentary phenotype, enlarged lymph nodes, enlarged thymus medulla, growth/size/body region phenotype, hunched posture, increased CD8-positive, alpha-beta T cell number, increased effector memory CD4-positive, alpha-beta T cell number, increased effector memory CD8-positive, alpha-beta T cell number, increased intestinal adenoma incidence, increased neutrophil cell number, increased T cell derived lymphoma incidence, increased T cell proliferation, muscle phenotype, no abnormal phenotype detected, premature death, ruffled hair, shortened RR interval, shortened ST segment [+]
View all ortholog results at Monarch