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Summary Expression Phenotypes Gene Literature (954) GO Terms (5) Nucleotides (271) Proteins (68) Interactants (2352) Wiki

tbxt     T-box transcription factor T

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased length of anterior-posterior axis (4 sources), abnormal gastrulation (3 sources), abnormal head morphology (3 sources), abnormal tail morphology (2 sources), abnormally delayed closure of blastopore (2 sources), abnormal bending of anterior-posterior axis (1 source), abnormal bending of tail (1 source), abnormal incomplete closing of the neural tube (1 source), abnormal tail bud morphology (1 source), abnormally anterioralized embryo (1 source), decreased size of the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tbxt assayed (112 sources)
Computed annotations: tbxt manipulated (6 sources), tbxt assayed (36 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + tbxt MO (3 sources), Xtr Wt + tbxt MO (3 sources), Xtr Wt + vegt MO + eomes MO + tbxt MO + tbxt.2 MO (3 sources), Xtr.Wt + tbxt MO + tbxt.2 MO (2 sources), Xla Wt + dntbxt-EnR (1 source), Xtr Wt + tbxt MO + tbxt.2 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (2 sources): Abnormal vertebral morphology, Absence of the sacrum

View all ortholog results at Monarch