mapk1 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (793)

XB-GENEPAGE-479466

Gene Symbol: mapk1 Gene Name: mitogen-activated protein kinase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: mapk1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (73 sources): abnormal Meckel's cartilage morphology, abnormal T cell subpopulation ratio, abnormal cerebral cortex morphology, abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal developmental patterning, abnormal enzyme/coenzyme level, abnormal extrinsic tongue muscle morphology, abnormal mandible morphology, abnormal mandibular angle morphology, abnormal maternal nurturing, abnormal nest building behavior, abnormal neuron differentiation, abnormal nursing, abnormal placenta development, abnormal placenta labyrinth morphology, abnormal placenta vasculature, abnormal placental labyrinth vasculature morphology, abnormal polar trophectoderm morphology, abnormal positive T cell selection, abnormal proximal-distal axis patterning, abnormal response to novel object, abnormal response to novelty, abnormal rostral-caudal axis patterning, abnormal social investigation, abnormal spatial learning, abnormal thymus morphology, abnormal tongue muscle morphology, abnormal trophoblast layer morphology, abnormal visceral endoderm morphology, absent ectoplacental cone, absent extraembryonic ectoderm, behavior/neurological phenotype, cardiac hypertrophy, craniofacial phenotype, decreased CD4-positive, alpha beta T cell number, decreased T cell proliferation, decreased anxiety-related response, decreased body size, decreased cardiac muscle contractility, decreased cardiac output, decreased double-positive T cell number, decreased embryo size, decreased fibroblast proliferation, disorganized extraembryonic tissue, embryonic growth retardation, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality during organogenesis, complete penetrance, failure of palatal shelf elevation, impaired contextual conditioning behavior, impaired cued conditioning behavior, increased aggression towards mice, increased cardiomyocyte apoptosis, increased double-positive T cell number, increased myocardial infarct size, lethality throughout fetal growth and development, complete penetrance, mandible hypoplasia, neonatal lethality, complete penetrance, nervous system phenotype, perinatal lethality, incomplete penetrance, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, preweaning lethality, incomplete penetrance, short maxilla, small Meckel's cartilage, small mandible, small mandibular condyloid process, social withdrawal, taste/olfaction phenotype, thin cerebral cortex, thin myocardium, thin placenta labyrinth, transmission ratio distortion [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (73 sources): abnormal Meckel's cartilage morphology, abnormal T cell subpopulation ratio, abnormal cerebral cortex morphology, abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal developmental patterning, abnormal enzyme/coenzyme level, abnormal extrinsic tongue muscle morphology, abnormal mandible morphology, abnormal mandibular angle morphology, [+]