| Monarch Ortholog Phenotypes
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Human (1 source):
Ischemic stroke
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Mouse (28 sources):
abnormal Leydig cell differentiation,
abnormal apoptosis,
abnormal cerebellar molecular layer,
abnormal lymph node medulla morphology,
abnormal mammary gland epithelium morphology,
abnormal mammary gland morphology,
abnormal neuron differentiation,
abnormal pituitary intermediate lobe morphology,
abnormal thymus size,
cortical renal glomerulopathies,
enlarged lymph nodes,
increased B cell derived lymphoma incidence,
increased T cell derived lymphoma incidence,
increased body size,
increased bone marrow cell number,
increased bronchioalveolar stem cell number,
increased lung adenoma incidence,
increased lung tumor incidence,
increased mammary gland tumor incidence,
increased pituitary adenoma incidence,
increased renal carcinoma incidence,
increased spleen white pulp amount,
increased testis tumor incidence,
lymphoid hyperplasia,
mammary gland hyperplasia,
pituitary gland hyperplasia,
premature death,
spleen hyperplasia
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.