Monarch Ortholog Phenotypes
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Human (8 sources):
Lacrimal duct stenosis,
Nail dystrophy,
Nephritis,
Nephropathy,
Pretibial blistering,
Reduced beta/alpha synthesis ratio,
Sensorineural hearing impairment,
Stage 5 chronic kidney disease
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Mouse (40 sources):
abnormal T cell proliferation,
abnormal bone marrow cell number,
abnormal glomerular capillary endothelium morphology,
abnormal glomerular capillary morphology,
abnormal glomerular endothelium fenestra morphology,
abnormal hair follicle morphology,
abnormal kidney morphology,
abnormal podocyte morphology,
abnormal proximal convoluted tubule morphology,
abnormal renal glomerular capsule morphology,
abnormal renal glomerulus basement membrane morphology,
abnormal renal glomerulus morphology,
abnormal vascular endothelial cell migration,
abnormal vascular endothelial cell physiology,
absent podocyte foot process,
absent podocyte slit diaphragm,
cardiovascular system phenotype,
decreased angiogenesis,
decreased incidence of induced tumors,
decreased incidence of tumors by chemical induction,
decreased keratinocyte migration,
decreased keratinocyte proliferation,
decreased podocyte number,
decreased tumor growth/size,
dilated proximal convoluted tubule,
dilated renal tubules,
glomerular crescent,
granular kidney,
hearing/vestibular/ear phenotype,
increased keratinocyte migration,
increased mesangial cell number,
increased renal glomerulus basement membrane thickness,
integument phenotype,
kidney degeneration,
podocyte foot process effacement,
premature death,
renal cast,
renal glomerular synechia,
renal/urinary system phenotype,
thin epidermis
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View all ortholog results at Monarch
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