| Monarch Ortholog Phenotypes
|
|
Human (18 sources):
Abnormality of neutrophils,
Atrial fibrillation,
Biventricular hypertrophy,
Chest pain,
Dilated cardiomyopathy,
Dyspnea,
EMG abnormality,
Elevated circulating creatine kinase concentration,
Hypertrophic cardiomyopathy,
Left anterior fascicular block,
[+]
|
Mouse (20 sources):
abnormal cardiac muscle contractility,
abnormal cardiac muscle relaxation,
abnormal heart echocardiography feature,
abnormal heart left ventricle pressure,
abnormal myocardial fiber morphology,
abnormal myocardial fiber physiology,
abnormal sympathetic nervous system physiology,
behavioral despair,
cardiac interstitial fibrosis,
decreased cardiac muscle relaxation,
decreased heart weight,
decreased lean body mass,
enlarged heart atrium,
increased anxiety-related response,
increased cardiac muscle contractility,
increased cardiac stroke volume,
increased total body fat amount,
papillary muscle hypertrophy,
preweaning lethality, complete penetrance,
thick ventricular wall
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.