nrp1 Phenotypes

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Phenotypes

Gene Literature (146)

Nucleotides (141)

Interactants (688)

XB-GENEPAGE-480687

Gene Symbol: nrp1 Gene Name: neuropilin 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: nrp1 assayed (3 sources)
Computed annotations: nrp1 assayed (7 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (1 source): Tetralogy of Fallot
Mouse (42 sources): abnormal accessory olfactory bulb morphology, abnormal aortic arch and aortic arch branch attachment, abnormal axon guidance, abnormal brain vasculature morphology, abnormal cerebral cortex pyramidal cell morphology, abnormal coronary artery morphology, abnormal coronary vessel morphology, abnormal dendritic cell physiology, abnormal dorsal aorta morphology, abnormal dorsal root ganglion morphology, abnormal facial motor nucleus morphology, abnormal first pharyngeal arch artery morphology, abnormal fourth pharyngeal arch artery morphology, abnormal induced retina neovascularization, abnormal pharyngeal arch artery morphology, abnormal retina blood vessel morphology, abnormal retina blood vessel pattern, abnormal retina vasculature morphology, abnormal second pharyngeal arch artery morphology, abnormal sixth pharyngeal arch artery morphology, abnormal spinal nerve morphology, abnormal third pharyngeal arch artery morphology, abnormal vascular development, cardiovascular system phenotype, decreased angiogenesis, decreased body size, decreased neuron number, decreased tumor growth/size, dilated heart atrium, disorganized yolk sac vascular plexus, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, failure of vascular branching, nervous system phenotype, perinatal lethality, complete penetrance, postnatal lethality, postnatal lethality, incomplete penetrance, premature death, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, vascular smooth muscle hypoplasia, vision/eye phenotype [+]
View all ortholog results at Monarch