Abnormality of retinal pigmentation, Abnormality of skin pigmentation, Abnormality of the abdominal wall, Abnormality of the dentition, Abnormality of the hepatic vasculature, Abnormality of the liver, Abnormality of the metacarpal bones, Abnormality of the musculature, Abnormality of the upper urinary tract, Absent fingernail, Absent toenail, Adenomatous colonic polyposis, Adrenocortical adenoma, Adrenocortical carcinoma, Agenesis of corpus callosum, Alternating esotropia, Ampulla of Vater carcinoma, Anasarca, Anemia, Anorexia, Arthralgia, Ascites, Astrocytoma, Ataxia, Axillary freckling, Basal cell carcinoma, Bone pain, Brain neoplasm, Breast carcinoma, Budd-Chiari syndrome, Cafe-au-lait spot, Carcinoma, Carious teeth, Cataract, Cerebellar medulloblastoma, Chest pain, Colon cancer, Congenital hypertrophy of retinal pigment epithelium, Constipation, Constitutional symptom, Convex nasal ridge, Crossed fused renal ectopia, Delayed eruption of teeth, Desmoid tumors, Diarrhea, Downslanted palpebral fissures, Duodenal adenocarcinoma, Duodenal polyposis, Dyspnea, Ectropion, Elbow dislocation, Elevated hepatic transaminase, Ependymoma, Epidermoid cyst, Epigastric pain, Epiretinal membrane, Eruption failure, Esophageal carcinoma, Esophageal varix, Fatigue, Fever, Fibroadenoma of the breast, Fibroma, Fibrosarcoma, Finger syndactyly, Foot oligodactyly, Frontal bossing, Gastrointestinal carcinoma, Gastrointestinal hemorrhage, Glioblastoma multiforme, Glioma, Gray matter heterotopia, Headache, Hearing impairment, Hematochezia, Hemobilia, Hepatic encephalopathy, Hepatic necrosis, Hepatoblastoma, Hepatocellular carcinoma, Hepatomegaly, Hereditary nonpolyposis colorectal carcinoma, High, narrow palate, Hip dislocation, Hydronephrosis, Hyperbilirubinemia, Hypercalcemia, Hypermelanotic macule, Hyperpigmentation of the fundus, Hyperpigmentation of the skin, Hypertelorism, Hypoalbuminemia, Hypodontia, Hypoglycemia, Hypokalemia, Hyponatremia, Hypoplasia of the radius, Hypoplasia of the ulna, Hypotension, Hypothyroidism, Increased intracranial pressure, Increased level of L-fucose in urine, Intellectual disability, moderate, Internal hemorrhage, Intestinal obstruction, Intestinal polyposis, Irregular hyperpigmentation, Jaundice, Keloids, Laryngomalacia, Leukemia, Limitation of joint mobility, Lipoma, Liver abscess, Lymphoma, Malabsorption, Malar flattening, Medulloblastoma, Melena, Metabolic alkalosis, Micrognathia, Micromelia, Micronodular cirrhosis, Multiple gastric polyps, Multiple lipomas, Multiple unerupted teeth, Myalgia, Nausea, Neoplasm, Neoplasm of the central nervous system, Neoplasm of the pancreas, Neoplasm of the skin, Neoplasm of the stomach, Neuroblastoma, Nystagmus, Odontoma, Oligodactyly, Osteolysis, Osteoma, Papillary thyroid carcinoma, Papilledema, Pedal edema, Pilomatrixoma, Pituitary adenoma, Polycythemia, Poor appetite, Portal hypertension, Prominent forehead, Proptosis, Prostate cancer, Protruding ear, Ptosis, Radioulnar synostosis, Renal agenesis, Renal cell carcinoma, Renal hypoplasia, Renal hypoplasia/aplasia, Rhabdomyosarcoma, Sarcoma, Scoliosis, Sepsis, Short nose, Short philtrum, Short thumb, Small intestine carcinoid, Soft tissue neoplasm, Spinal cord compression, Stomach cancer, Subacute progressive viral hepatitis, Subcutaneous nodule, Supernumerary tooth, Syndactyly, Synostosis of carpal bones, Synostosis of joints, Thrombocytopenia, Thrombocytosis, Thyroid carcinoma, Thyroid nodule, Toe syndactyly, Transitional cell carcinoma of the bladder, Type II diabetes mellitus, Uterine leiomyosarcoma, Venous insufficiency, Visual acuity no light perception, Visual impairment, Vomiting, Weight loss, obsolete Mood changes

abnormal cell proliferation, abnormal chondrocyte morphology, abnormal colon morphology, abnormal craniofacial morphology, abnormal cranium morphology, abnormal crypts of Lieberkuhn morphology, abnormal developmental patterning, abnormal digestive system morphology, abnormal effector T cell morphology, abnormal egg cylinder morphology, abnormal embryo development, abnormal embryo size, abnormal embryonic epiblast morphology, abnormal embryonic tissue morphology, abnormal endocardial heart tube morphology, abnormal endochondral bone ossification, abnormal enterocyte proliferation, abnormal feces composition, abnormal floor plate morphology, abnormal foregut morphology, abnormal forelimb morphology, abnormal gut flora balance, abnormal hair follicle bulb morphology, abnormal hair follicle development, abnormal hair follicle morphology, abnormal hair follicle orientation, abnormal head development, abnormal hindbrain development, abnormal hindlimb morphology, abnormal humerus morphology, abnormal intestinal epithelium morphology, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, abnormal intestine development, abnormal keratinocyte differentiation, abnormal large intestine crypts of Lieberkuhn morphology, abnormal limb development, abnormal mammary gland development, abnormal mandible morphology, abnormal mesendoderm development, abnormal nursing, abnormal ovarian follicle morphology, abnormal ovarian folliculogenesis, abnormal oviduct morphology, abnormal pancreas development, abnormal pregnancy, abnormal primitive node morphology, abnormal skeleton development, abnormal small intestine crypts of Lieberkuhn morphology, abnormal thoracic cavity morphology, abnormal thymus morphology, abnormal tooth development, abnormal tumor morphology, abnormal tumor pathology, abnormal urinary bladder urothelium morphology, abnormal vagina epithelium morphology, absent corpus luteum, absent forebrain, absent male preputial gland, absent mandible, absent mature ovarian follicles, absent neural folds, absent sternum, absent teeth, absent upper incisors, adrenal gland hyperplasia, aneuploidy, arrested T cell differentiation, cardia bifida, cellular phenotype, colon polyps, corneal epithelium hyperplasia, decreased NK T cell number, decreased body length, decreased body size, decreased embryo size, decreased fetal size, decreased hematocrit, decreased intestinal adenoma incidence, decreased macrophage cell number, decreased pancreatic beta cell mass, decreased pancreatic islet number, decreased splenocyte number, decreased thymocyte number, decreased tumor growth/size, delayed hair appearance, dermal cyst, embryonic lethality, embryonic lethality between implantation and placentation, embryonic lethality between implantation and somite formation, incomplete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, embryonic-extraembryonic boundary constriction, enhanced osteoblast differentiation, enlarged mesenteric lymph nodes, epidermal cyst, extended life span, gastric polyps, gastrointestinal tract polyps, homeostasis/metabolism phenotype, hunched posture, incomplete embryo turning, increased adenoma incidence, increased apoptosis, increased cell proliferation, increased circulating tumor necrosis factor level, increased colon adenoma incidence, increased desmoid tumor incidence, increased double-negative T cell number, increased ear pigmentation, increased gastrointestinal tumor incidence, increased granulosa cell tumor incidence, increased hepatocellular carcinoma incidence, increased incidence of induced tumors, increased incidence of tumors by chemical induction, increased interferon-gamma secretion, increased interleukin-4 secretion, increased intestinal adenoma incidence, increased liver tumor incidence, increased mammary adenocarcinoma incidence, increased mammary gland tumor incidence, increased metastatic potential, increased organ/body region tumor incidence, increased osteoma incidence, increased prostaglandin level, increased prostate gland adenocarcinoma incidence, increased prostate intraepithelial neoplasia incidence, increased renal cystadenoma incidence, increased reproductive system tumor incidence, increased skin tumor incidence, increased small intestinal crypt cell apoptosis, increased stomach tumor incidence, increased trichoepithelioma incidence, increased tumor growth/size, increased tumor incidence, intestinal hemorrhage, kinked tail, lethality throughout fetal growth and development, incomplete penetrance, liver hyperplasia, mammary gland hyperplasia, neonatal lethality, complete penetrance, no abnormal phenotype detected, ovary atrophy, perinatal lethality, complete penetrance, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, prenatal lethality, complete penetrance, reproductive system phenotype, rostral body truncation, rostral-caudal axis duplication, salivary gland epithelial hyperplasia, short hair, short tail, short vibrissae, skin ridges, small stomach, small thymus, split notochord, underdeveloped hair follicles, uterus atrophy