| Monarch Ortholog Phenotypes
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Human (1 source):
Eczematoid dermatitis
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Mouse (27 sources):
abnormal blood-brain barrier function,
abnormal insulin-like growth factor I level,
abnormal interleukin-6 secretion,
abnormal lymphocyte physiology,
abnormal macrophage physiology,
abnormal tooth root resorption,
abnormal tumor vascularization,
abnormal vascular wound healing,
decreased acute inflammation,
decreased circulating interleukin-1 beta level,
decreased interferon-gamma secretion,
decreased interleukin-1 beta secretion,
decreased interleukin-2 secretion,
decreased interleukin-4 secretion,
decreased metastatic potential,
decreased sensitivity to induced morbidity/mortality,
decreased susceptibility to Togaviridae infection,
decreased susceptibility to Togaviridae infection induced morbidity/mortality,
decreased susceptibility to experimental autoimmune myasthenia gravis,
decreased susceptibility to injury,
decreased susceptibility to type IV hypersensitivity reaction,
decreased susceptibility to viral infection,
decreased tumor growth/size,
decreased tumor necrosis factor secretion,
immune system phenotype,
impaired febrile response,
increased susceptibility to bacterial infection induced morbidity/mortality
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.