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Summary Expression Phenotypes Gene Literature (155) GO Terms (12) Nucleotides (139) Proteins (54) Interactants (1002) Wiki

bmp2     bone morphogenetic protein 2

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal axis specification (2 sources), decreased length of anterior-posterior axis (2 sources), decreased size of the head (2 sources), abnormal head morphology (1 source), abnormal pathway-restricted SMAD protein phosphorylation (1 source), absent foregut (1 source), absent liver primordium (1 source), absent lung primordium (1 source), absent ventral pancreatic bud (1 source), decreased length of trunk (1 source), decreased size of the foregut (1 source), edematous embryo (1 source), obsolete duplicated anatomical axis (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: bmp2 manipulated (9 sources), bmp2 assayed (7 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + bmp2 MO (9 sources), Xla Wt + Hsa.BMP2 (2 sources), Xla Wt + bmp2 (1 source), Xla Wt + bmp2 + dvl3 MO (1 source), Xla Wt + kcp + bmp2 (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (52 sources): 11 pairs of ribs, 2-3 toe syndactyly, Anteverted nares, Aplasia/Hypoplasia of the middle phalanx of the 2nd finger, Aplasia/Hypoplasia of the middle phalanx of the 5th finger, Broad forehead, Broad hallux, Clinodactyly of the 5th finger, Conductive hearing impairment, Delayed skeletal maturation, [+]
Mouse (41 sources): abnormal cardiac epithelial to mesenchymal transition, abnormal cardiac jelly morphology, abnormal chorion morphology, abnormal fetal atrioventricular canal morphology, abnormal heart development, abnormal heart position or orientation, abnormal myocardium layer morphology, abnormal proamniotic cavity morphology, abnormal vascular development, abnormal vertebral column morphology, [+]

View all ortholog results at Monarch