| Monarch Ortholog Phenotypes
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Human (6 sources):
Cleft palate,
Hereditary nonpolyposis colorectal carcinoma,
Neoplasm of the stomach,
Renal cell carcinoma,
Transitional cell carcinoma of the bladder,
Uterine leiomyosarcoma
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Mouse (20 sources):
abnormal blood cell morphology/development,
abnormal brain development,
abnormal cell adhesion,
abnormal forebrain development,
abnormal heart development,
abnormal hindbrain development,
abnormal placenta labyrinth morphology,
abnormal placental labyrinth vasculature morphology,
abnormal vitelline vasculature morphology,
delayed brain development,
embryo tissue necrosis,
embryonic growth retardation,
embryonic lethality during organogenesis, complete penetrance,
enhanced wound healing,
increased fibroblast cell migration,
no abnormal phenotype detected,
open neural tube,
pale yolk sac,
prenatal lethality, complete penetrance,
thin ventricular wall
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.