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Summary Expression Phenotypes Gene Literature (60) GO Terms (6) Nucleotides (111) Proteins (60) Interactants (2316) Wiki

esr1     estrogen receptor 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: esr1 manipulated (2 sources), esr1 assayed (2 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + esr1-GR + DEX (1 source), Xla Wt + esr1-GR + DEX + CHX (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (24 sources): Abnormal circulating hormone concentration, Absence of pubertal development, Absence of secondary sex characteristics, Acanthosis nigricans, Acne, Breast carcinoma, Breast hypoplasia, Coronary artery atherosclerosis, Delayed epiphyseal ossification, Delayed skeletal maturation, [+]
Mouse (191 sources): abnormal bone marrow cell number, abnormal bone marrow cell physiology, abnormal bone mineralization, abnormal branching of the mammary ductal tree, abnormal cell migration, abnormal chondrocyte physiology, abnormal class switch recombination, abnormal cremaster muscle morphology, abnormal definitive hematopoiesis, abnormal efferent ductules of testis morphology, [+]

View all ortholog results at Monarch