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Summary Expression Phenotypes Gene Literature (29) GO Terms (11) Nucleotides (73) Proteins (43) Interactants (360) Wiki

nkx2-2     NK2 homeobox 2

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: nkx2-2 assayed (3 sources)
Computed annotations: nkx2-2 assayed (3 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (26 sources): abnormal neuron specification, abnormal pancreatic beta cell differentiation, abnormal pancreatic islet morphology, abnormal serotonergic neuron morphology, absent oligodendrocytes, absent pancreatic beta cells, decreased PP cell number, decreased glucagon secretion, decreased insulin secretion, decreased pancreatic alpha cell number, [+]