| Monarch Ortholog Phenotypes
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Mouse (26 sources):
abnormal neuron specification,
abnormal pancreatic beta cell differentiation,
abnormal pancreatic islet morphology,
abnormal serotonergic neuron morphology,
absent oligodendrocytes,
absent pancreatic beta cells,
decreased glucagon secretion,
decreased insulin secretion,
decreased pancreatic alpha cell number,
decreased PP cell number,
disorganized pancreatic islets,
endocrine/exocrine gland phenotype,
growth/size/body region phenotype,
homeostasis/metabolism phenotype,
increased circulating glucose level,
increased motor neuron number,
increased pancreatic alpha cell number,
increased pancreatic epsilon cell number,
no abnormal phenotype detected,
postnatal lethality,
postnatal lethality, complete penetrance,
premature death,
reduced female fertility,
reduced male fertility,
reproductive system phenotype,
small pancreatic islets
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.