| Monarch Ortholog Phenotypes
|
Human (54 sources):
2-3 toe syndactyly,
2nd-5th toe middle phalangeal hypoplasia,
3-4 finger syndactyly,
3-4 toe syndactyly,
4-5 metacarpal synostosis,
4-5 toe syndactyly,
6 metacarpals,
Absent distal interphalangeal creases,
Aplasia/Hypoplasia of the distal phalanx of the hallux,
Brachydactyly,
Broad distal phalanx of the hallux,
Broad distal phalanx of the thumb,
Broad hallux,
Camptodactyly,
Camptodactyly of finger,
Carpal synostosis,
Clinodactyly of the 5th finger,
Contracture of the proximal interphalangeal joint of the 5th finger,
Cutaneous finger syndactyly,
Enlarged proximal interphalangeal joints,
Finger syndactyly,
Frontal bossing,
Hallux valgus,
Joint contracture of the hand,
Joint hyperflexibility,
Macrocephaly,
Mesoaxial hand polydactyly,
Metacarpal synostosis,
Metatarsal synostosis,
Moderately short stature,
Multiple impacted teeth,
Oligodactyly,
Postaxial foot polydactyly,
Preaxial foot polydactyly,
Round face,
Short 5th metacarpal,
Short clavicles,
Short distal phalanx of finger,
Short fifth metatarsal,
Short metacarpal,
Short metatarsal,
Short middle phalanx of the 2nd finger,
Short middle phalanx of the 5th finger,
Short phalanx of finger,
Short stature,
Straight clavicles,
Symphalangism affecting the phalanges of the hand,
Syndactyly,
Toe syndactyly,
Type D brachydactyly,
Type E brachydactyly,
Ulnar deviation of finger,
Upper limb asymmetry,
Y-shaped metacarpals
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Mouse (24 sources):
abnormal digit development,
abnormal embryonic tissue morphology,
abnormal forelimb morphology,
abnormal hallux morphology,
abnormal internal anal sphincter morphology,
abnormal limb development,
abnormal metacarpal bone morphology,
abnormal phalanx morphology,
abnormal seminal vesicle morphology,
abnormal smooth muscle morphology,
abnormal tarsal bone morphology,
absent female preputial gland,
absent male preputial gland,
decreased metacarpal bone number,
decreased metatarsal bone number,
delayed bone ossification,
delayed endochondral bone ossification,
endocrine/exocrine gland phenotype,
interdigital webbing,
limbs/digits/tail phenotype,
polysyndactyly,
reduced male fertility,
sacral vertebral fusion,
short radius
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.