Monarch Ortholog Phenotypes
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Human (4 sources):
Abnormal electroretinogram,
Blindness,
Glaucoma,
Macular dystrophy
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Mouse (59 sources):
abdominal aorta aneurysm,
abnormal Bruch membrane morphology,
abnormal abdominal aorta morphology,
abnormal aorta wall morphology,
abnormal apoptosis,
abnormal artery morphology,
abnormal blood vessel elastic tissue morphology,
abnormal blood vessel physiology,
abnormal branching involved in terminal bronchiole morphogenesis,
abnormal bronchiole morphology,
abnormal cardiac muscle relaxation,
abnormal choroid vasculature morphology,
abnormal involution of the mammary gland,
abnormal kidney morphology,
abnormal lactation,
abnormal learning/memory/conditioning,
abnormal liver lobule morphology,
abnormal pulmonary alveolus morphology,
abnormal pulmonary alveolus wall morphology,
abnormal retina blood vessel morphology,
abnormal retina pigment epithelium morphology,
abnormal spatial learning,
abnormal systemic arterial blood pressure,
abnormal vascular branching morphogenesis,
aortitis,
behavior/neurological phenotype,
cardiac fibrosis,
cardiac hypertrophy,
cardiovascular system phenotype,
cellular phenotype,
decreased cardiac muscle contractility,
decreased circulating glucose level,
decreased lean body mass,
decreased left ventricle developed pressure,
decreased left ventricle systolic pressure,
decreased susceptibility to induced hypothermia,
decreased systemic arterial blood pressure,
decreased vasodilation,
decreased ventricle muscle contractility,
dilated heart left ventricle,
dilated terminal bronchiole tube,
endocrine/exocrine gland phenotype,
hunched posture,
impaired liver regeneration,
impaired lung alveolus development,
increased body temperature,
increased carbon dioxide production,
increased hepatocyte apoptosis,
increased oxygen consumption,
increased response of heart to induced stress,
increased sensitivity to induced morbidity/mortality,
increased startle reflex,
increased susceptibility to injury,
increased tumor necrosis factor secretion,
overexpanded pulmonary alveoli,
premature death,
renal/urinary system phenotype,
respiratory system phenotype,
ruffled hair
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View all ortholog results at Monarch
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