tnnt2 Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (17)

Nucleotides (175)

Interactants (242)

XB-GENEPAGE-482613

Gene Symbol: tnnt2 Gene Name: troponin T2, cardiac type

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tnnt2 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (14 sources): Abnormality of neutrophils, Atrial fibrillation, Cardiomyopathy, Congestive heart failure, Dilated cardiomyopathy, EMG abnormality, Elevated circulating creatine kinase concentration, Hypertrophic cardiomyopathy, Left ventricular hypertrophy, Left ventricular noncompaction, Lipoatrophy, Myopathy, Palmoplantar keratoderma, Sensorineural hearing impairment [+]
Mouse (47 sources): abnormal Z line morphology, abnormal action potential, abnormal cardiac muscle contractility, abnormal cardiac muscle relaxation, abnormal embryonic tissue morphology, abnormal heart development, abnormal heart echocardiography feature, abnormal myocardial fiber morphology, abnormal myocardial fiber physiology, abnormal sarcomere morphology, absent atrioventricular cushions, absent heartbeat, cardiac hypertrophy, cardiac interstitial fibrosis, decreased cardiac muscle contractility, decreased cardiac muscle relaxation, decreased embryo size, decreased heart left ventricle size, decreased heart left ventricle weight, decreased heart weight, decreased left ventricle developed pressure, decreased left ventricle systolic pressure, decreased myocardial fiber number, decreased survivor rate, decreased ventricle muscle contractility, dilated heart, dilated heart atrium, dilated heart left ventricle, dilated sarcoplasmic reticulum, disorganized myocardium, embryonic growth retardation, embryonic lethality between somite formation and embryo turning, incomplete penetrance, embryonic lethality during organogenesis, complete penetrance, enlarged heart atrium, failure of heart looping, heart inflammation, increased cardiac muscle contractility, myocardial fiber degeneration, myocardial fiber disarray, no abnormal phenotype detected, perinatal lethality, complete penetrance, perivascular fibrosis, premature death, prolonged HV interval, prolonged QRS complex duration, small heart, small myocardial fiber [+]
View all ortholog results at Monarch