cdk1 Phenotypes

Phenotypes

XB-GENEPAGE-482749

Gene Symbol: cdk1 Gene Name: cyclin-dependent kinase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cdk1 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (22 sources): abnormal DNA replication, abnormal blastocyst morphology, abnormal cell nucleus count, abnormal cell nucleus morphology, abnormal hepatocyte morphology, abnormal lens development, abnormal lens epithelium morphology, abnormal lens fiber morphology, abnormal mitosis, abnormal response to injury, arrest of male meiosis, decreased cell proliferation, decreased hepatocyte number, decreased hepatocyte proliferation, decreased incidence of induced tumors, decreased tumor growth/size, early cellular replicative senescence, embryonic lethality before implantation, complete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, failure of zygotic cell division, polyploidy [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (22 sources): abnormal DNA replication, abnormal blastocyst morphology, abnormal cell nucleus count, abnormal cell nucleus morphology, abnormal hepatocyte morphology, abnormal lens development, abnormal lens epithelium morphology, abnormal lens fiber morphology, abnormal mitosis, abnormal response to injury, [+]