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Summary Expression Phenotypes Gene Literature (242) GO Terms (8) Nucleotides (225) Proteins (62) Interactants (1337) Wiki

smad2     SMAD family member 2

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally ventralized embryo (2 sources), decreased length of anterior-posterior axis (2 sources), abnormal axis elongation (1 source), abnormal bending of anterior-posterior axis (1 source), abnormal bending of tail (1 source), abnormal development of embryo (1 source), abnormal gastrulation (1 source), abnormal head morphology (1 source), abnormal tail morphology (1 source), absent cement gland (1 source), decreased length of tail (1 source), decreased size of the tail (1 source), obsolete duplicated dorsal-ventral axis (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: smad2 manipulated (9 sources)
Computed annotations: smad2 assayed (1 source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + smad2 MO (3 sources), Xla Wt + smad2 + animal cap explant (2 sources), Xla Wt + foxh1 + smad2 (1 source), Xla Wt + pias4 + smad2 + animal cap explant (1 source), Xla Wt + smad2 (1 source), Xla Wt + smad2 (1 source), Xla Wt + smad2 (1 source), Xla Wt + smad2 + animal cap explant (1 source), Xla Wt + smad2 MO (1 source), Xla Wt + smad2 MO (1 source), Xla Wt + smad2-VP16 (1 source), Xla Wt + dnsmad2 (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (82 sources): abnormal Meckel's cartilage morphology, abnormal Purkinje cell dendrite morphology, abnormal anterior definitive endoderm morphology, abnormal cell differentiation, abnormal cell migration, abnormal cell morphology, abnormal cerebellar foliation, abnormal cerebellar granule cell migration, abnormal cerebellar granule cell morphology, abnormal cerebellum vermis lobule IX morphology, [+]