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Summary Expression Phenotypes Gene Literature (642) GO Terms (12) Nucleotides (235) Proteins (78) Interactants (1940) Wiki

bmp4     bone morphogenetic protein 4

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
partially ventralized embryo (3 sources), wholly ventralized embryo (2 sources), abnormal tail morphology (1 source), abnormal ventral trunk morphology (1 source), decreased size of the embryo (1 source), decreased size of the head (1 source), edematous ventral trunk (1 source), wholly dorsalized tadpole (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: bmp4 manipulated (20 sources), bmp4 assayed (14 sources)
Computed annotations: bmp4 manipulated (1 source), bmp4 assayed (10 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + bmp4 (3 sources), Xla Wt + bmp4 MO (3 sources), Xla Wt + bmp4 (2 sources), Xla Wt + bmp4 + animal cap explant (2 sources), Xla Wt + bmp4 + CHX + animal cap explant (2 sources), Xla Wt + Hsa.BMP4 (2 sources), Xla Wt + dnbmp4 (2 sources), Xtr Wt + bmp4 (2 sources), Xtr Wt + bmp4 MO (2 sources), Xla Wt + bmp4 (1 source), Xla Wt + bmp4 + animal cap explant (1 source), Xla Wt + bmp4 + animal cap explant (1 source), Xla Wt + bmp4 + animal cap explant (1 source), Xla Wt + bmp4 + rspo2 + animal cap explant (1 source), Xla Wt + Hsa.BMP4 (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (82 sources): Abnormal cerebral white matter morphology, Abnormality of the cervical spine, Abnormality of the ear, Abnormality of the genital system, Abnormality of the hand, Abnormality of the hypothalamus-pituitary axis, Abnormality of the skeletal system, Absent speech, Adrenal hypoplasia, Agenesis of corpus callosum, [+]
Mouse (162 sources): abnormal Wolffian duct morphology, abnormal allantois morphology, abnormal amniotic cavity morphology, abnormal angiogenesis, abnormal aortic arch and aortic arch branch attachment, abnormal artery morphology, abnormal atrioventricular cushion morphology, abnormal canal of Schlemm morphology, abnormal cardiac mesenchyme morphology, abnormal cardiac outflow tract development, [+]

View all ortholog results at Monarch