Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (82) GO Terms (14) Nucleotides (154) Proteins (50) Interactants (1262) Wiki
XB-GENEPAGE-483192

hesx1     HESX homeobox 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased size of the head (1 source), edematous ventral trunk (1 source), wholly ventralized embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: hesx1 assayed (1 source)
Computed annotations: hesx1 assayed (29 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + hesx1 MO (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (109 sources): Abdominal distention, Abnormal cardiovascular system morphology, Abnormal digit morphology, Abnormal morphology of female internal genitalia, Abnormal prolactin level, Abnormality of secondary sexual hair, Abnormality of the face, Abnormality of the hypothalamus-pituitary axis, Abnormality of the orbital region, Abnormality of the voice, [+]
Mouse (34 sources): abnormal Rathke's pouch development, abnormal adenohypophysis morphology, abnormal craniofacial morphology, abnormal dorsal telencephalic commissure morphology, abnormal eye development, abnormal forebrain development, abnormal frontonasal prominence morphology, abnormal midbrain-hindbrain boundary development, abnormal nasal cavity morphology, abnormal nasal pit morphology, [+]

View all ortholog results at Monarch