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XB-GENEPAGE-483330
pdx1 pancreatic and duodenal homeobox 1
Anatomical Phenotypes
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increased size of the pancreas (2 sources), abnormal bending of tail (1 source), abnormal dorsal fin margin morphology (1 source), abnormal duodenum morphology (1 source), abnormal stomach morphology (1 source), abnormal ventral fin margin morphology (1 source), decreased size of the duodenum (1 source), decreased size of the stomach (1 source) |
Expression Phenotypes
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Manual annotations: pdx1 manipulated (4 sources), pdx1 assayed (35 sources) |
Computed annotations: pdx1 assayed (5 sources) |
Experiments (Reagents)
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Xla Wt + pdx1-GR + ptf1a-GR + DEX (4 sources), Xla Wt + pdx1 MO (1 source), Xla Wt + pdx1 MO + ptf1a MO (1 source) |
Monarch Ortholog Phenotypes
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Human (73 sources): Abnormal circulating C-peptide concentration, Abnormal heart morphology, Abnormal insulin level, Abnormal oral glucose tolerance, Abnormality of the ear, Abnormality of the genitourinary system, Abnormality of the immune system, Abnormality of the kidney, Abnormality of the upper urinary tract, Anteverted nares, [+] |
Mouse (52 sources): abnormal PP cell morphology, abnormal bile duct development, abnormal duodenum morphology, abnormal embryo size, abnormal enteroendocrine cell morphology, abnormal foregut morphology, abnormal liver development, abnormal mitochondrial physiology, abnormal pancreas development, abnormal pancreatic acinar cell morphology, [+] |
View all ortholog results at Monarch |