fzd7 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (117)

XB-GENEPAGE-483730

Gene Symbol: fzd7 Gene Name: frizzled class receptor 7

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
obsolete abnormal histone phosphorylation (5 sources), abnormal foregut morphology (3 sources), abnormal gastrulation (3 sources), abnormal regulation of cell size (3 sources), decreased length of anterior-posterior axis (3 sources), increased size of the cell (3 sources), abnormal bending of anterior-posterior axis (2 sources), abnormal bending of tail (2 sources), abnormal head morphology (2 sources), absent liver (2 sources), absent stomach (2 sources), decreased size of the dorsal marginal zone (2 sources), increased size of the foregut (2 sources), obsolete abnormally edematous foregut (2 sources), abnormal alimentary system morphology (1 source), abnormal archenteron morphology (1 source), abnormal Brachet's cleft morphology (1 source), abnormal canonical Wnt signaling pathway (1 source), abnormal cell adhesion (1 source), abnormal cell morphology (1 source), abnormal dorsal trunk (1 source), abnormal endoderm morphology (1 source), abnormal foregut endoderm morphology (1 source), abnormal hindgut morphology (1 source), abnormal incomplete closing of the neural tube (1 source), abnormal JNK cascade (1 source), abnormally decreased coiling of small intestine (1 source), abnormally decreased length of alimentary system (1 source), abnormally decreased length of intestine (1 source), abnormally delayed closure of blastopore (1 source), abnormal tail bud morphology (1 source), abnormal tail morphology (1 source), abnormal whole organism morphology (1 source), absent pancreas (1 source), dead whole organism (1 source), decreased cell adhesion in foregut (1 source), decreased cell population proliferation in foregut endoderm (1 source), decreased length of tail (1 source), decreased size of the actin cytoskeleton (1 source), decreased size of the archenteron (1 source), decreased size of the eye (1 source), decreased size of the heart (1 source), decreased size of the tail (1 source), increased size of the foregut endoderm (1 source), obsolete abnormally edematous alimentary system (1 source), obsolete abnormally edematous pharyngeal region (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

obsolete abnormal histone phosphorylation (5 sources), abnormal foregut morphology (3 sources), abnormal gastrulation (3 sources), abnormal regulation of cell size (3 sources), decreased length of anterior-posterior axis (3 sources), increased size of the cell (3 sources), abnormal bending of anterior-posterior axis (2 sources), abnormal bending of tail (2 sources), abnormal head morphology (2 sources), absent liver (2 sources), absent stomach (2 sources), decreased size of the dorsal marginal zone (2 sources), increased size of the foregut (2 sources), obsolete abnormally edematous foregut (2 sources), abnormal alimentary system morphology (1 source), abnormal archenteron morphology (1 source), abnormal Brachet's cleft morphology (1 source), abnormal canonical Wnt signaling pathway (1 source), abnormal cell adhesion (1 source), abnormal cell morphology (1 source), abnormal dorsal trunk (1 source), abnormal endoderm morphology (1 source), abnormal foregut endoderm morphology (1 source), abnormal hindgut morphology (1 source), abnormal incomplete closing of the neural tube (1 source), abnormal JNK cascade (1 source), abnormally decreased coiling of small intestine (1 source), abnormally decreased length of alimentary system (1 source), abnormally decreased length of intestine (1 source), abnormally delayed closure of blastopore (1 source), abnormal tail bud morphology (1 source), abnormal tail morphology (1 source), abnormal whole organism morphology (1 source), absent pancreas (1 source), dead whole organism (1 source), decreased cell adhesion in foregut (1 source), decreased cell population proliferation in foregut endoderm (1 source), decreased length of tail (1 source), decreased size of the actin cytoskeleton (1 source), decreased size of the archenteron (1 source), decreased size of the eye (1 source), decreased size of the heart (1 source), decreased size of the tail (1 source), increased size of the foregut endoderm (1 source), obsolete abnormally edematous alimentary system (1 source), obsolete abnormally edematous pharyngeal region (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fzd7 manipulated (24 sources)
Computed annotations: fzd7 assayed (5 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + fzd7 MO (11 sources), Xla Wt + fzd7 MO (5 sources), Xla Wt + fzd7 MO (5 sources), Xla Wt + fzd7 MO + sdc4 MO (4 sources), Xla Wt + fzd7 MO (3 sources), Xla Wt + fzd7 MO + sdc4 MO (3 sources), Xtr Wt + fzd7 MO (3 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO + BIO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xtr Wt + fzd7 MO (2 sources), Xla Wt + caHsa.MAPK8 + fzd7 MO + DEX (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO + sdc4 MO (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + fzd7 MO + DEX (1 source)

Experiments (Reagents)

These are short form descriptions of experiments using reagents targeting the gene of interest.

Xla Wt + fzd7 MO (11 sources), Xla Wt + fzd7 MO (5 sources), Xla Wt + fzd7 MO (5 sources), Xla Wt + fzd7 MO + sdc4 MO (4 sources), Xla Wt + fzd7 MO (3 sources), Xla Wt + fzd7 MO + sdc4 MO (3 sources), Xtr Wt + fzd7 MO (3 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO (2 sources), Xla Wt + fzd7 MO + BIO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xtr Wt + fzd7 MO (2 sources), Xla Wt + caHsa.MAPK8 + fzd7 MO + DEX (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO (1 source), Xla Wt + fzd7 MO + sdc4 MO (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + hsp70:xfz7;hsp70:GFP3 + HS (1 source), Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + fzd7 MO + DEX (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (2 sources): kinked tail, short tail