Cholelithiasis, Choriocapillaris atrophy, Cirrhosis, Clubbing, Congestive heart failure, Conjunctival telangiectasia, Cyanosis, Dyspnea, Eczema, Epistaxis, Esophageal varix, Fingerpad telangiectases, Gastrointestinal angiodysplasia, Gastrointestinal arteriovenous malformation, Gastrointestinal hemorrhage, Gastrointestinal telangiectasia, Hematemesis, Hematochezia, Hematuria, Hemoptysis, Hepatic arteriovenous malformation, Hepatic failure, Hypertension, Intestinal polyposis, Ischemic stroke, Lip telangiectasia, Melena, Microcytic anemia, Migraine, Mucosal telangiectasiae, Nail bed telangiectasia, Nasal mucosa telangiectasia, Nephrolithiasis, Palate telangiectasia, Peripheral arteriovenous fistula, Polycythemia, Portal hypertension, Pulmonary arterial hypertension, Pulmonary arteriovenous malformation, Pulmonary embolism, Retinal telangiectasia, Right-to-left shunt, Seizure, Spinal arteriovenous malformation, Spontaneous hematomas, Spontaneous, recurrent epistaxis, Subarachnoid hemorrhage, Telangiectasia of the skin, Tongue telangiectasia, Transient ischemic attack, Venous thrombosis, Visceral angiomatosis

abnormal heart layer morphology, abnormal hepatobiliary system morphology, abnormal intersomitic vessel morphology, abnormal lung vasculature morphology, abnormal myocardium layer morphology, abnormal physiological response to xenobiotic, abnormal sympathetic nervous system physiology, abnormal trabecula carnea morphology, abnormal vascular development, abnormal vascular smooth muscle morphology, abnormal vascular wound healing, abnormal visceral yolk sac morphology, abnormal vitelline vascular remodeling, abnormal vitelline vasculature morphology, absent atrioventricular cushions, absent vitelline blood vessels, cardiovascular system phenotype, decreased circulating angiotensin II level, decreased hematocrit, dilated dorsal aorta, dilated liver sinusoidal spaces, dilated pharyngeal arch arteries, dilated vasculature, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, enlarged pericardium, increased circulating adrenaline level, increased circulating noradrenaline level, increased vasodilation, large intestine hemorrhage, lethality throughout fetal growth and development, complete penetrance, lung hemorrhage, moribund, no abnormal phenotype detected, poor arterial differentiation, postnatal lethality, premature death, renal/urinary system phenotype, vascular smooth muscle hypotrophy